All of us Vs Keratoconus


Members Login
Chatbox
Please log in to join the chat!
Post Info TOPIC: Gene Therapy Primary Research


Phase Two

Status: Offline
Posts: 482
Date: Mon Jan 15 9:09 PM, 2007
Gene Therapy Primary Research
Permalink   
 


Efficient Non-Viral Ocular Gene Transfer with Compacted DNA Nanoparticles
(Published: December 20, 2006)


Copyright: 2006 Farjo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

"The eye is an excellent candidate for gene therapy as it is immune privileged and much of the disease-causing genetics are well understood. Towards this goal, we evaluated the efficiency of compacted DNA nanoparticles as a system for non-viral gene transfer to ocular tissues. ..."

"Taken together, our data suggest that this mode of gene therapy is applicable for multiple forms of ocular diseases. As intravitreal injection targets the tissues in the front of the eye, this mode of therapy could be widely applicable for corneal diseases such as cataracts and keratoconus...."

"This nanoparticle system shows tremendous promise as the basis for developing strategies to treat various diseases of the eye. ..."



Please Click Here

PLoS ONE (eISSN-1932-6203) is an international, peer-reviewed, open-access, online publication from the Public Library of Science (PLoS). PLoS ONE welcomes reports on primary research from any scientific discipline.

Public Library of Science
7 Portugal Place
Cambridge CB5 8AF UK
Phone: +44(0)1223 463 330
FAX: +44(0)1223 463 348
www.plos.org


__________________
Page 1 of 1  sorted by
 
Quick Reply

Please log in to post quick replies.

Post to Digg Post to Del.icio.us

www.kcfreedom.org

Knowledge Works