All of us Vs Keratoconus


Members Login
Chatbox
Please log in to join the chat!
Post Info TOPIC: crosslinking good eye


Executive

Status: Offline
Posts: 437
Date: Fri Apr 7 10:07 PM, 2006
crosslinking good eye
Permalink   
 


so guys I did crosslinking to my best eye this tuesday in Dortmund. At St Johannes Hospital, where Dr. Kohlhaas now works. Details will come later as my eye sight will be getting better.

-- Edited by Yarsky at 22:10, 2006-04-07

__________________
yarsky


Phase Two

Status: Offline
Posts: 484
Date: Fri Apr 7 11:14 PM, 2006
Permalink   
 

Yarsky my good and great friend... while you was away you was missed very much here... wishing you the a comfortable few days...  


...and after that you can throw away/or burn! that contact lens you are using so that you could have this treatment done... (Please write about that moment when you destroy that contact lens!!!!!!)


...I'm also happy for you as we might not all be lucky enough, like you, to be treated by the best!


Just write as much or as little as you want to mate... 


Great to have you back! 



__________________


Executive

Status: Offline
Posts: 164
Date: Sat Apr 8 3:40 PM, 2006
Permalink   
 

hey yarsky, hope it is going well! keep us updated mate!!!

__________________
yeup... it's me. :p


Executive

Status: Offline
Posts: 437
Date: Tue Apr 11 11:32 AM, 2006
Permalink   
 

Hi!

am back home, writing this without The Lens Janus 3T! Lol! It was of great help: without it I could not do the feat

The haze on the x_linked crnea is as it should be. Do not see well, as you understand. A couple of general important observations:

1. Dr.Kohlhaas told be that in his opinion the x_linking effect is temporary and may be gone in like decade, becuase a) the turn-over of collagen that brings away iduced cross_links b) the desease may be still present in the body. And thét probably the procedure may be reapeted in the future, when and if the effect is gone. I am and was conscious of this. It is better that KC reoccur, if it must, to the x_linked cornea than to the transplanted one.

2. As I was walking into the surgery room, a 14 year old boy was walking out, with his mother and grand mother. He had cross_linking done to both of his eyes. 14 year old boy from Atlanta, who came to Dortmund with his mom and grandmother frop the US. Dr; Kohlhaas told me last year that the majority of his KC patients were teens...I remembar last November, in Dresden, when we decided to wait, there was a girl in her late teens, with her mother, who did not decide to wait and did one eye. Well any way these are emotions. What is not emotions, is that the treatment protocle is now well established, in my opinion.

3. The crucial thing afetr the treatment: STUFF COPIOUSLY the eye with vitamine A ointment and the antibiotic drops that you are given after the procidure. This is the part of the patient"s responsability. Both are important. The eye should swim in this vit A ointment, for epithelial cells grow easier. I needed 4 full days to get it fully grown back. Probably whan you are younger (in his/her teens this takes 2-3 days). But I had it for 4 days with both eyes. It is important because the epithelium is a protective cell layer that blocks all bacterias. Anyway, one should better remain 4 complete days in a room and stuff periodically the eye with all these medications. I found it very-very usefull. Stay in room, indoors, relax take care of the eyes, oint them, and keep closed.


4. The therapeutic lens. The doctor who assists Dr Kohlhaas with cross-linking, put a therapeutic lens on my cross_linked cornea immediiatley after the procedure was over. The lens protects the eye from dust, etc and from the lids, from blinking: each blinking desturbs the frowing cells. So the lens was there for two complete days. Than it was taken away. The previous eye I did without the lens. I find the painfull ffeling during the night about the same. However probably one may easily open the eye with the lens than without to put in the ointments. So probably it is useful; Anyway during these 4 days the eye is closed: this is the nature. Interesting, after the lens was taken away, the eye started to generate a sort of glue. In the mornings of the 3d and 4th day it was difficult to open the eye. I find it very interestin for it was I thnk a protective glue: eye should be closed while the epithelium is not full grown: once the epithelium growth was copleted the gluing was naturally stopped. At the beginning I thought it was because of an infection, but the doctors told me not to be afraid, that all was going fine. So I slept easily.

5 What I found particularly handy and useful was a mirror that I bought before the travel. A mirror that increases the omage. In my case it was x 7 . So I used it to put the lesn in when needed and to stuff the eye with ointment when without lens. A small mirror, I bought it in a pharmacy. What was not handy at all it was a cane for the blind and malvoyants that I bought in a pharmacy to hedge myself if smth goes wrong with the lens. An what was handyand is actually now - it's a reading glass
x 3,5 . Very usefull thing when without lens. I also have glasses that I ordered last year, but they are out of measure and do not fit any more.

5. This time the post op development will be completeley gauged as I have all my orbscans before the treatment.

6. The haze aspect is not funny and, as Valeri wrote it last year in his posts, the vision is weak. But, being a researcher, I find it intriguing to observe how it will dissipate.

7. When it will dissipate I'll be able to say if I won or not with respect to the vision quality. However, I am conscious that I should wait for the results to be more pronounced somwhere in august.


-- Edited by Yarsky at 11:43, 2006-04-11

-- Edited by Yarsky at 23:46, 2006-04-16

__________________
yarsky


Phase Two

Status: Offline
Posts: 484
Date: Tue Apr 11 6:03 PM, 2006
Permalink   
 

I see from the map that your back in France... I hope you had a comfortable trip and thanks for your detailed post...


There is definately an active period to kc... usually the younger (teens, 20's, 30's) age group is the ones that should seriouly think about x linking so that kc can be disabled and progression "zapped"... progression of kc IS confused with what a contact lens does to a weakened cornea...


Generally speaking for a contact lens wearer, a more regular cornea, which x linking creates is one where a contact lens "fits" better on a strenghtened cornea also.


For those just diagnosed, where a rapid loss of vision can be avoided is helped with x linking.


Those who wear glasses or don't need no correction can be helped with the regression x linking gives some what.


Those, depending on the size and position of their cone, can be helped to get back in to glasses from contacts with x linking as already seen.


The list goes on...


If the strenghtening thats done, if it last's for decades or not can only be known in decades to come!... I personally think there is a formular to the progression of kc... true kc progression only happens i beleive at the intial stages of kc (for a time that can be zapped by the time at which x linking has already been proved to stop kc)... the other progression is once contact lenses comes in to the equation... look at me... don't wear contacts (but needed them)... vision stayed the same and even got bettter!!!!!!!! ... as kc "settled" and not forgetting as you get older ..like you told me mate... your inner lens gets thinner so vision improves some what if your myopic which kc creates (so your vision as you age can increase just a little... by just enough... its more than enough for me now!)


I think Kc just gets zapped of its progression and the cornea stays the same...


Catch ya soon mate... look forward to hearing from you...



-- Edited by QuintriX at 03:17, 2006-04-23

__________________


Executive

Status: Offline
Posts: 437
Date: Tue Apr 11 10:37 PM, 2006
Permalink   
 

hi;
yea, I think you've got to be right with that timing thing and to what the x_lincking does to keratoconus: zap and put it away. However, all this - to be seen in the future.

Now let me tell you another story, believe it or not...I had a long walk today, without the lens. I bought things and talked to people on the street - without the lens. I type it without the lens. I think that one week without the good eye and my worst started to see sharper. The reason being, possibly, that it "slept" when the good one was up. I mean the cornea is as it is, but the nerve and the whole mechanism was sort of sleeping... Now for the last week, to live, I used only the bad one with the lens or without...Probably it is the brain thing...A miracle anyway....The good eye meanwhile is getting better....It is gettig better faster than the bad one last year, I think...

__________________
yarsky


Phase Two

Status: Offline
Posts: 484
Date: Thu Apr 13 5:40 PM, 2006
Permalink   
 

I think you got regression of your kc after all this time!!!!!!!!!!!!!!!!!!!!!!!!! ...well done!!!!!!!!!


Also on another point... I think the thing that is forgotten is that not only is there links created but also, shrinkage of collegan does come in to the equation too by some degree... this is very helpful to us for the obvious reasons! ...both can only happen if all the elements are used.


So to cut a long story short... every part in the "scratch method" of X linking works well together... to create a very intelligent solution.


(Scratch>B2>UV>Links)= corneal strength


Every element is needed for the other elements to work properly (a lot of detail too much for this post... but its in all the other posts on x linking though)


God Bless!...Happy Easter!



-- Edited by QuintriX at 22:35, 2006-04-13

__________________


Executive

Status: Offline
Posts: 437
Date: Fri Apr 14 1:30 PM, 2006
Permalink   
 

Hi Quintrix,

the mechanism and the issue of collagene shrinkage is a bit obscure to me...can you develop, please? Physically I can see the following. Collagen is a protein, a macromolecule. Normally it is a a closely intewoven thing of three "threads". In cornea or skin or tendons, any tissue it is organaised in fibres. In cornea a fiber is a tough intrweaving of these blocs. Now, this is surrounded by the coatings of gelly like hydrophile proteoglycanes. I the procedure, the riboflavine gets inside the proteoglycanes coating, as inside a sponge. So after these 5 minutes of soaking the uva comes in. A quant of the uva hits forst a riboflavine molecile because avarything in the cornea is surrounded by this substance. The molecule gets exicted and forms a bond (sort of a bridge) between two macromolecules of collagen inside the fiber, I beleieve. Anyway it goes like this in places where two colagene macromolecules are close enough to each other. A spacing between two fibers is abour 64 nanometers. A diameter of a fiber is about 32 nanometers. The quaestion is what is the size of the riboflavine molecule? I believe it is about 100 nanometers. I think in this way a B2 molecule can be only between two fubres...Anyway, if a uva quant reaches a collagen molecules - what happens? It hits her. segment. This segement gets exiited and comes closer to another segement...So this is like shrinkage...But why is it beneficial for us? Another mechanism is when uva does not reach the collagen. In this case the bridges may just shorten the the distance between too fibres. In this way cornea shrinks a bit. And in bothways it should be seen on pachymetriys...Why is it beneficial than if pachymetry can go a bit down? I am not sure there is the shrinkage.....

__________________
yarsky
1 2 3  >  Last»  | Page of 3  sorted by
 
Quick Reply

Please log in to post quick replies.

Post to Digg Post to Del.icio.us

www.kcfreedom.org

Knowledge Works