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Post Info TOPIC: Anyone know the history of the development of crosslinking?


Veteran Member

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Posts: 33
Date: Tue Jun 12 9:12 PM, 2012
Anyone know the history of the development of crosslinking?
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Somewhere on the Internet I read about the scientific history of crosslinking. Maybe it had to do with animals.  I know I read it somewhere, but cannot find it again.

When people hear that the crosslinking procedure involves Vitamin B2 (riboflavin) and ultra-violet light, they ask how this was discovered.   While it won't much affect what happens with my adult child (the patient), I'd still like to know about this discovery.  

There is so much uncertainty involved in the results of crosslinking and the lack of USA published studies, that I would like to know something that is close to definite, like the history of the procedure.

I do know that the crosslinking procedure on patients was initiated in Dresden.  It is the part about how it got to that point that peaks my curiosity.

Thanks,

Emily_G



-- Edited by Emily_G on Tuesday 12th of June 2012 09:15:10 PM

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Registered Nurse

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Posts: 6
Date: Wed Jun 13 12:30 AM, 2012
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Hi Emily,

Seems like we are regularly seeing each other on the forum. The surgery was invented by an ophthalmologist called Theo Seiler. I have seen him in lectures. Supposedly it was inspired by some dentistry procedures where they used a UV light with Riboflavin to strengthen the dentistry procedure. The theory is also used in dermatology as well I think.

Check out this link for some intro information on it.

http://www.healio.com/Ophthalmology/Cornea-External-Disease/news/print/ocular-surgery-news-europe-edition/%7B235FEC91-B1D1-4874-AA70-A8CFD950A15F%7D/Corneal-cross-linking-shows-increasingly-good-results-gains-popularity-stimulates-research

Regards,

Isobel



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Executive

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Posts: 155
Date: Wed Jun 13 4:14 PM, 2012
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Additionally to that I have read that they use crosslinking to stiffen heart values when thats needed, and they have been doing this for a very long time.

The other story I heard was there was some scientists working of a treatment to stop winkles occuring as a skin product for this...and a scientist who was walking passed said "you know, we could use that on Keratoconus!"



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Veteran Member

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Date: Thu Jun 14 7:50 PM, 2012
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Thanks for your interesting and informative replies.

Emily



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