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Evaluating the reliability of the responses of large language models to keratoconus-related questions
M Kayabaşı, S Köksaldı, C Durmaz Engin - Clinical and Experimental Optometry, 2024
Clinical relevance Artificial intelligence has undergone a rapid evolution and large
language models (LLMs) have become promising tools for healthcare, with the
ability of providing human-like responses to questions. The capabilities of these …
language models (LLMs) have become promising tools for healthcare, with the
ability of providing human-like responses to questions. The capabilities of these …
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[PDF] Prevalence and demographic pro le of keratoconus among high school students in Kenya
ZA Rashid, VR Moodley, KP Mashige
… Keratoconus (KC) is a corneal disorder that usually presents in adolescence. The
prevalence of KC in Western countries [1–6] and North and East Asia [7–10] is
generally < 1.3% with one exception where Chan et al. [11] recently reported a …
prevalence of KC in Western countries [1–6] and North and East Asia [7–10] is
generally < 1.3% with one exception where Chan et al. [11] recently reported a …
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Keratoconus
RB Singh, S Koh, N Sharma, FA Woreta, F Hafezi… - Nature Reviews Disease …, 2024
… Interestingly, in a study in Lebanon, 12% of patients with keratoconus had a
family history of keratoconus, and eye rubbing was not an … of association between
keratoconus and eye rubbing 52,89 . Thus, a two-hit model has been suggested for …
family history of keratoconus, and eye rubbing was not an … of association between
keratoconus and eye rubbing 52,89 . Thus, a two-hit model has been suggested for …
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[HTML] Visual rehabilitation using rigid gas permeable contact lenses after femtosecond laser-assisted minimally invasive lamellar keratoplasty in patients with keratoconus
J Zhang, X Lin, Z Li, X Zhong, W Shi, X Du, H Gao - Scientific Reports, 2024
This study aims to observe the clinical efficacy and safety of rigid gas permeable
corneal contact lenses (RGP-CLs) wearing after femtosecond laser-assisted
minimally invasive lamellar keratoplasty (FL-MILK) in progressive and advanced …
corneal contact lenses (RGP-CLs) wearing after femtosecond laser-assisted
minimally invasive lamellar keratoplasty (FL-MILK) in progressive and advanced …
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[HTML] Evaluation of parameters for early detection of pediatric keratoconus
SH Zhao, C Berkowitz, H Ralay Ranaivo, K Laurenti… - BMC ophthalmology, 2024
Background Keratoconus in children is often more severe and rapidly progressive
compared to adults. While Scheimpflug imaging (Pentacam) improves screening,
there are no established pediatric guidelines. Due to challenges in diagnosis, we …
compared to adults. While Scheimpflug imaging (Pentacam) improves screening,
there are no established pediatric guidelines. Due to challenges in diagnosis, we …
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[HTML] Impact of Keratoconus on Contrast Sensitivity
LY Zhen, FS Barodawala - Journal of Health Science and Medical Research, 2024
Objective: Keratoconus (KC) disrupts corneal shape, leading to irregular
astigmatism and increased higher-order aberrations (HOA), ultimately affecting
visual quality. While visual acuity (VA) remains the standard, its limitations in early …
astigmatism and increased higher-order aberrations (HOA), ultimately affecting
visual quality. While visual acuity (VA) remains the standard, its limitations in early …
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Retraction Note: Detection and evaluation of Keratoconus (corneal topography) by using the image classifier techniques
R Kanimozhi, R Gayathri - 2024
Retraction Note: Detection and evaluation of Keratoconus (corneal topography) by
using the image classifier techniques | Soft Computing … Retraction Note: Detection
and evaluation of Keratoconus (corneal topography) by using the image classifier …
using the image classifier techniques | Soft Computing … Retraction Note: Detection
and evaluation of Keratoconus (corneal topography) by using the image classifier …
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[HTML] Late corneal ectasia after penetrating and deep anterior lamellar keratoplasty for keratoconus
B Yüksel, AE Kocakaya, T Küsbeci, F Gümüş - International Journal of …, 2024
… keratoconus recurrence in the donor button, progression of keratoconus in the
host rim with consequent graft-host interface thinning and misalignment, or less likely;
grafting a donor cornea with undiagnosed keratoconus… late ectasia after …
host rim with consequent graft-host interface thinning and misalignment, or less likely;
grafting a donor cornea with undiagnosed keratoconus… late ectasia after …
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[HTML] Comparison of the quantitative contrast sensitivity function between early keratoconus and normal eyes
Y Xian, Y Ye, L Sun, Y Shen, X Zhang, ZL Lu, X Zhou… - BMC Ophthalmology, 2024
To compare the characteristics of the quantitative contrast sensitivity function (qCSF)
in eyes with early keratoconus (Early-KC) and normal control (NC) eyes and
investigate the associated factors. A cross-sectional study. This study included 43 …
in eyes with early keratoconus (Early-KC) and normal control (NC) eyes and
investigate the associated factors. A cross-sectional study. This study included 43 …
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[HTML] Computational approaches for identifications of altered ion channels in keratoconus
KB Gaikwad, JS Babu, KTS Parthasarathi, J Narayanan… - Eye, 2024… give crucial information to understand keratoconus aetiology [26, 27]. There is no
study to the best of our knowledge that describes alterations in ion channels in
patients with keratoconus. Here, the transcriptome of patients with keratoconus was …
study to the best of our knowledge that describes alterations in ion channels in
patients with keratoconus. Here, the transcriptome of patients with keratoconus was …
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[HTML] Agreement in anterior segment measurements between swept-source optical coherence and dual Scheimpflug tomography devices in keratoconus eyes
Y Lee, JY Oh, HJ Choi, MK Kim, CH Yoon - Scientific Reports, 2024… This study analyzed the agreement between Casia 2 and Galilei G6 in
keratoconus. For most parameters used to diagnose keratoconus and assess
disease progression, the agreement between the two devices was not excellent and …
keratoconus. For most parameters used to diagnose keratoconus and assess
disease progression, the agreement between the two devices was not excellent and …
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[HTML] Tear levels of apoptotic, matrix-degrading and antioxidant biomarkers in patients with and without keratoconus: A cross sectional study
AM Roszkowska, U Camellin, F Franchina… - Contact Lens and Anterior Eye… keratoconus and 33 were age-matched healthy subjects. The linear combination
of the three tear biomarkers levels (AUC = 0.811; CI 95 %: 0.712–0.911) accurately
indicated the existence of keratoconus; … ) were significantly associated with a …
of the three tear biomarkers levels (AUC = 0.811; CI 95 %: 0.712–0.911) accurately
indicated the existence of keratoconus; … ) were significantly associated with a …
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[PDF] Patient evaluated economic impact of keratoconus in New Zealand
L Angelo, A Gokul, I Samuels, CNJ McGhee, M Ziaei - Clinical and Experimental …, 2024… by keratoconus subjects, to estimate the lifetime per capita cost and the total costs
of keratoconus per year in Auckland, New Zealand. … the total out-of-pocket spend
for keratoconus is less in New Zealand despite having a higher prevalence of …
of keratoconus per year in Auckland, New Zealand. … the total out-of-pocket spend
for keratoconus is less in New Zealand despite having a higher prevalence of …
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[PDF] Keratoconus: modern diagnostic approach
L Pateyuk - Journal of Clinical Practice, 2024… Keratoconus is an ectatic … the keratoconus diagnosis, outlines current
approaches to patients examining and diagnostics results assessing. The clinical
manifestations (complaints, anamnesis data, visometry and autorefractokeratometry …
approaches to patients examining and diagnostics results assessing. The clinical
manifestations (complaints, anamnesis data, visometry and autorefractokeratometry …
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Thyroid gland dysfunction and keratoconus
OM Said, M Iqbal, A El-Massry, ME Elgharieb, M Mady… - … hypothesis discovery and …, 2024… Background: The association between keratoconus and thyroid gland dysfunction
(TGD) remains controversial. We aimed to determine the frequency of keratoconus
among patients with laboratory-confirmed, treatment-naive TGD compared with that …
(TGD) remains controversial. We aimed to determine the frequency of keratoconus
among patients with laboratory-confirmed, treatment-naive TGD compared with that …
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After all, Doctor: Does my Child have Keratoconus or Not?
FBD Da Silva - Highlights of Ophthalmology, 2024Establishing the diagnosis of a disease that can impact the vision and life of a
patient (such as keratoconus) is a moment of great responsibility. Therefore,
ophthalmology has been looking for to integrate the results provided by the most …
patient (such as keratoconus) is a moment of great responsibility. Therefore,
ophthalmology has been looking for to integrate the results provided by the most …
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[HTML] Optimizing UV-A Irradiation Profiles in Crosslinking for Keratoconus: Comparison of Outcomes After Standard Accelerated and Topography-Guided Protocols
T Cortinhal, J Gil, A Rosa, MJ Quadrado, J Murta - Revista Sociedade Portuguesa de …, 2024INTRODUÇÃO: O objetivo do presente estudo é comparar resultados refrativos e
tomográficos do crosslinking corneano no queratocone, utilizando laser excimer
para remoção do epitélio e irradiação central uniforme (C-CXL) ou irradiação …
tomográficos do crosslinking corneano no queratocone, utilizando laser excimer
para remoção do epitélio e irradiação central uniforme (C-CXL) ou irradiação …
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Pediatric Keratoconus
Y Gupta, C Devi, K Priyadarshini, S Mandal, R Tandon… - Survey of Ophthalmology, 2024
Keratoconus is a common pediatric corneal disease, leading to vision impairment
and amblyopia. Compared to its adult counterpart, pediatric keratoconus has an
advanced presentation, rapid progression, higher incidence of complications such …
and amblyopia. Compared to its adult counterpart, pediatric keratoconus has an
advanced presentation, rapid progression, higher incidence of complications such …
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[HTML] Cessation of contact lenses prior to corneal tomography for keratoconus monitoring: results from a clinician survey
C McAlinden, D Lockington - Eye, 2024
… Corneal tomography is essential in diagnosing and monitoring corneal ectasias,
including keratoconus. Monitoring may be necessary to … precision is more
challenging in eyes with keratoconus [2]. Visual improvement in eyes keratoconus is …
including keratoconus. Monitoring may be necessary to … precision is more
challenging in eyes with keratoconus [2]. Visual improvement in eyes keratoconus is …
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[HTML] Mendelian randomization reveals that abnormal lipid metabolism mediates the causal relationship between body mass index and keratoconus
J Wang, F Liu, D Gong, J Su, F Zheng, S Ding, J Mo… - Scientific Reports, 2024
Previous studies suggest that a high body mass index (BMI) may be a risk factor for
keratoconus (KC), but the causal relationship remains unclear. This study used
Mendelian randomization (MR) to investigate this connection and explore the …
keratoconus (KC), but the causal relationship remains unclear. This study used
Mendelian randomization (MR) to investigate this connection and explore the …
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Air Pollution and the Prevalence of Keratoconus: Is There a Connection?
T Jurkiewicz, AS Marty - Ophthalmic Epidemiology, 2024
… Keratoconus is a progressive, asymmetrical corneal ectasia with multifactorial
origin. Three identified risk factors for keratoconus include … Other factors like
pollution would play a role in the physiopathology of keratoconus. In this study we …
origin. Three identified risk factors for keratoconus include … Other factors like
pollution would play a role in the physiopathology of keratoconus. In this study we …
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Transcriptomic analysis of Keratoconus in Han Chinese patients: Insights into differential gene expression and ethnic-specific patterns
Y Li, Y Dai, J Xu, J Zhang - Experimental Eye Research, 2024
Keratoconus (KC) is a progressive corneal ectatic disorder with a high prevalence
among Asians. This study aimed to explore the differential gene expression patterns
in Han Chinese patients with KC, focusing on mRNAs and long noncoding RNAs (lncRNAs) …
among Asians. This study aimed to explore the differential gene expression patterns
in Han Chinese patients with KC, focusing on mRNAs and long noncoding RNAs (lncRNAs) …
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Experimental Models for Keratoconus: Insights and challenges
S Shankar, R Deshmukh, T Pingali, R Sonar, S Basu… - Experimental Eye Research, 2024
… Keratoconus, a progressive corneal disorder characterized by the thinning and
conical protrusion of the cornea because of collagen degradation, poses significant
challenges to patients and clinicians. Most successful animal models in keratoconus …
conical protrusion of the cornea because of collagen degradation, poses significant
challenges to patients and clinicians. Most successful animal models in keratoconus …
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[HTML] Comparison of a Scheimpflug imaging with other screening indices in diagnosing keratoconus and keratoconus suspect
Y Huo, R Xie, X Chen, S Li, H Zou, Y Liu, Y Wang - Scientific Reports, 2024
Keratoconus (KC) is an irreversible blinding eye disease; therefore, early screening
of KC suspects (KCS) is crucial for protecting patients' quality of life. Scheimpflug
imaging is a commonly used screening device in clinical practice. We aimed to …
of KC suspects (KCS) is crucial for protecting patients' quality of life. Scheimpflug
imaging is a commonly used screening device in clinical practice. We aimed to …
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[HTML] Inflammatory and genomic interactions within keratoconus susceptible patients: a nationwide registered case–control study
F Doroodgar, F Alizadeh, S Niazi, SM Razavi, N Jalilian… - Eye and Vision, 2024
Purpose This study aimed to investigate the association between variants in the
interleukin (IL)-1 gene cluster and susceptibility to keratoconus (KC) in an Iranian
population. Methods In the case group, there were 188 KC patients diagnosed by …
interleukin (IL)-1 gene cluster and susceptibility to keratoconus (KC) in an Iranian
population. Methods In the case group, there were 188 KC patients diagnosed by …
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Associations between endothelial cell characteristics and corneal topography findings in different stages of keratoconus
AH Reyhan, AS Karadağ, A Şimşek - International Ophthalmology, 2024
… This study aimed to compare and correlate specular microscope indices and
corneal topography indices in different stages of keratoconus… progression of
keratoconus. It appears that as keratoconus index values increase, NUM may …
corneal topography indices in different stages of keratoconus… progression of
keratoconus. It appears that as keratoconus index values increase, NUM may …
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[PDF] One-Year Results of a Posterior Chamber Toric Phakic Intraocular Lens Implantation in Patients with Keratoconus
K Balparda, M Escobar Giraldo, YM Valencia Gómez… - Clinical Ophthalmology, 2024
Purpose To determine clinical and refractive results after the implantation of EyeCryl
Phakic Toric intraocular lens in patients with stable keratoconus. Methods The study
included all patients diagnosed with keratoconus who underwent implantation of an …
Phakic Toric intraocular lens in patients with stable keratoconus. Methods The study
included all patients diagnosed with keratoconus who underwent implantation of an …
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Keratoconus classification using a novel convolutional neural network architecture and corneal curvature maps
LO de Oliveira, FM de Carvalho Taguchi… - Applications of Machine …, 2024
… keratoconus, 91.24% for keratoconus, and 99.58% for severe keratoconus).
Additionally, the model achieved AUC scores of 0.97, 0.92, 0.90, 0.98, and 0.94 for
normal eye, suspect eye, subclinical keratoconus, keratoconus, and severe …
Additionally, the model achieved AUC scores of 0.97, 0.92, 0.90, 0.98, and 0.94 for
normal eye, suspect eye, subclinical keratoconus, keratoconus, and severe …
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Enhanced keratoconus care through optometry-led services at the West of England Eye Unit, Exeter
J Isaac, E Tutchings, Z Smith, L Isaac, C Newitt, A Loft… - Eye, 2024
… -led' keratoconus (KC) management at The Birmingham and Midland Eye Centre (BMEC)
[1]. … 2: Flowchart depicting outcomes of new suspect keratoconus referrals into the
new optometry … -led KC service provides a prompt and holistic approach to …
[1]. … 2: Flowchart depicting outcomes of new suspect keratoconus referrals into the
new optometry … -led KC service provides a prompt and holistic approach to …
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[PDF] Change in Tear Layer Thickness under Scleral Contact Lenses in Keratoconus Patients and Normal Cornea Volunteers
A Thuangtong, N Taetrongchit, R Kemahayung - Siriraj Medical Journal, 2024
Objective: To quantify rate of post-lens tear thickness change under scleral contact
lenses in keratoconus patients and normal cornea volunteers. Materials and
Methods: We conducted a prospective observational study where semi-scleral …
lenses in keratoconus patients and normal cornea volunteers. Materials and
Methods: We conducted a prospective observational study where semi-scleral …
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[PDF] Efficacy of KeraVio with Irradiation via Violet Light-Emitting Glasses without the Administration of Riboflavin Drops for Progressive Keratoconus Treatment
H Kobashi, T Kumanomido, T Ide, N Kato, J Shimazaki… - 2024
KeraVio is a new portable corneal cross-linking (CXL) treatment modality in which
violet light (VL)-emitting spectacles are used along with topical transepithelial
riboflavin. We preliminarily identified endogenous riboflavin in the human cornea …
violet light (VL)-emitting spectacles are used along with topical transepithelial
riboflavin. We preliminarily identified endogenous riboflavin in the human cornea …
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Is there a relationship between the keratoconus and the peripapillary choroidal vasculature?
K Gahramanov, M Unlu, F Ozer, H Sener, K Erkilic - International Ophthalmology, 2024
Purpose To evaluate the peripapillary/parapapillary choroidal vascular parameters
in the keratoconus (KC) and to determine the relationship between topography
parameters and the peripapillary/parapapillary choroidal vascular parameters …
in the keratoconus (KC) and to determine the relationship between topography
parameters and the peripapillary/parapapillary choroidal vascular parameters …
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[HTML] Save Sight Keratoconus Registry Study: Transepithelial versus Epithelium-off Corneal Crosslinking
GA Borchert, H Kandel, A Gupta, JY Chen, Y Kerdraon… - AJO International, 2024
Purpose Corneal collagen crosslinking (CXL) is the primary treatment for
progressive keratoconus and can be performed with the epithelium on or off.
Evidence is needed to guide clinicians and patients on whether they should have …
progressive keratoconus and can be performed with the epithelium on or off.
Evidence is needed to guide clinicians and patients on whether they should have …
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[PDF] A Theoretical Approach for Diagnosing Keratoconus Using Purkinje Image Geometry: An Accessible Method for Low-Cost and Early Detection
M Sharifzadeh - 2024
… keratoconus severity, with higher scores indicating greater deviation from normal
corneal profiles. Conclusions: This study presents a promising, low-cost approach to
diagnosing keratoconus … diagnostic tool for early keratoconus detection …
corneal profiles. Conclusions: This study presents a promising, low-cost approach to
diagnosing keratoconus … diagnostic tool for early keratoconus detection …
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[PDF] Reliability of Scheimpflug versus anterior segment optical coherence tomography after epithelial_off crosslinking in keratoconus
H Elgazzar, AS Mostafa, TK Eleiwa, KM Elgabry - Benha Medical Journal, 2024
… Second, these topography-based techniques have trouble differentiating between
keratoconus … These may cause false diagnosis of keratoconus or potential to hide
real keratoconus. … each keratoconus grade, and there was excellent reliability for …
keratoconus … These may cause false diagnosis of keratoconus or potential to hide
real keratoconus. … each keratoconus grade, and there was excellent reliability for …
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[PDF] Keratoconus Disease Prediction by Utilizing Feature-Based Recurrent Neural Network
SH Musa, QJM Alhaidar, MMB Elmi
… for detecting Keratoconus from clinical … with keratoconus six and twelve months
after the Kraring ring implantation using RNN are 9.82% and 9.29%, respectively.
The average error of estimating characteristics of predicting the visual characteristics …
after the Kraring ring implantation using RNN are 9.82% and 9.29%, respectively.
The average error of estimating characteristics of predicting the visual characteristics …
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[HTML] EyeWorld Journal Club review:"Prediction of the small aperture intraocular lens on visual acuity in patients with keratoconus"
R Wallace, S Gupta
Methods This study was a retrospective chart review of all patients with keratoconus
seen at Storm Eye Institute, Medical University of South Carolina between July 2016
and October 2022. The IC-8 Apthera IOL received pre-market approval from the FDA …
seen at Storm Eye Institute, Medical University of South Carolina between July 2016
and October 2022. The IC-8 Apthera IOL received pre-market approval from the FDA …
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Comment on: intraocular pressure after combined photorefractive keratectomy and corneal collagen cross linking for keratoconus
SK Chaurasiya, R Ray, M Singh - International Ophthalmology, 2024
… Ethnic and genetic factors can influence the presentation and progression of eye
conditions like keratoconus [3]… keratoconus. This information can be valuable for
understanding the impact of surgical procedures on IOP and guiding clinical …
conditions like keratoconus [3]… keratoconus. This information can be valuable for
understanding the impact of surgical procedures on IOP and guiding clinical …
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Trio-based whole-exome sequencing of 200 Chinese patients with keratoconus
X Li, Y Yao, S Xing, YH Zheng, Y Zhou, X Yu, J Su… - Experimental Eye Research, 2024
… in 200 patients with sporadic keratoconus and their unaffected parents. The
variants identified in candidate genes for keratoconus were analyzed using multiple
bioinformatics tools. Finally, we identified 7 variants in 5 candidate genes for …
variants identified in candidate genes for keratoconus were analyzed using multiple
bioinformatics tools. Finally, we identified 7 variants in 5 candidate genes for …
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[PDF] Harnessing Corneal Stromal Regeneration for Vision Restoration: A Comprehensive Review of the Emerging Treatment Techniques for Keratoconus
Z Javed, S Daigavane - Cureus, 2024
Keratoconus is a progressive corneal disorder characterized by thinning and conical
protrusion, leading to visual impairment that often necessitates advanced treatment
strategies. Traditional management options, including corrective lenses, corneal …
protrusion, leading to visual impairment that often necessitates advanced treatment
strategies. Traditional management options, including corrective lenses, corneal …
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Depression among Keratoconus (KC) Patients: A Systematic Review and Meta-Analysis
R Moshfeghinia, A Arman, N Sobhi… - Frontiers in Public Health
Background: Keratoconus (KC) is a chronic corneal disease that typically presents in
early adulthood, and may potentially result in poor mental health in affected
individuals. The evidence regarding the association of depression with KC is …
early adulthood, and may potentially result in poor mental health in affected
individuals. The evidence regarding the association of depression with KC is …
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Exploring the Accuracy and Readability of ChatGPT in Providing Information to Patients With Keratoconus
E Assayag, D Zadok, L Berkovitz, Y Weill - Journal of Pediatric Ophthalmology & …, 2024
Patients with keratoconus may lack sufficient understanding of their illness. The
authors assessed the accuracy and readability of ChatGPT (OpenAI) responses to
common questions regarding keratoconus and found that the provided data are …
authors assessed the accuracy and readability of ChatGPT (OpenAI) responses to
common questions regarding keratoconus and found that the provided data are …
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Multi-dataset identification of innovative feature genes and molecular mechanisms in keratoconus
N Lyu, Y Dai, J Wu, Y Fan, Z Lyu, J Gu, J Cheng, J Xu - Journal of cellular and …, 2024
This study aimed to identify feature genes and explore the molecular mechanisms of
keratoconus (KC). We downloaded data files from NCBI GEO public database. The
Limma package was used for differential expression analysis of gene profiles. Lasso …
keratoconus (KC). We downloaded data files from NCBI GEO public database. The
Limma package was used for differential expression analysis of gene profiles. Lasso …
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Distinguishing Subclinical from Clinical Keratoconus by Corneal Measurements
C Nicula, KU Horvath, AP Nicula, AE Bulboacă… - Frontiers in Medicine
Purpose: The study aimed to determine the stability of topographic and tomographic
indices measured with Pentacam and to evaluate the biomechanical parameters
measured with Corvis ST in the diagnosis of subclinical (sKCN) and clinical …
indices measured with Pentacam and to evaluate the biomechanical parameters
measured with Corvis ST in the diagnosis of subclinical (sKCN) and clinical …
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Prediction model for treatment outcomes 3 years after corneal cross-linking for keratoconus
Y Li, C Qiao, H Wang, Y Liu, MY Qi, L Ke, Y Zhou… - International Ophthalmology, 2024
… indicators to evaluate the progress of keratoconus or the postoperative efficacy of
CXL [5, 10,… keratoconus in our hospital who were treated with either accelerated
transepithelial or epithelium-off CXL between 2014 and 2019. The inclusion criteria …
CXL [5, 10,… keratoconus in our hospital who were treated with either accelerated
transepithelial or epithelium-off CXL between 2014 and 2019. The inclusion criteria …
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[HTML] Cochrane corner: artificial intelligence for keratoconus
EWW Tiong, SH Liu, DSJ Ting - Eye, 2024
… Keratoconus typically presents in the second to third … keratoconus [1]. This can
be aided by several advanced analytical techniques such as Belin Ambrosio
Enhanced Ectasia Display (for keratoconus detection) and Belin ABCD progression …
be aided by several advanced analytical techniques such as Belin Ambrosio
Enhanced Ectasia Display (for keratoconus detection) and Belin ABCD progression …
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Static magnetic field effects on the secondary structure and elasticity of collagen molecules; a possible biophysical approach to treat keratoconus
M Akbari, H Mobasheri, F Noorizadeh, SH Daryabari… - … and Biophysical Research …, 2024
Type I collagen is among the major extracellular proteins that play a significant role
in the maintenance of the cornea's structural integrity and is essential in cell
adhesion, differentiation, growth, and integrity. Here, we investigated the effect of …
in the maintenance of the cornea's structural integrity and is essential in cell
adhesion, differentiation, growth, and integrity. Here, we investigated the effect of …
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Role of genes in the pathogenesis of keratoconus
C Liu, F Yang - International Eye Science, 2024
Keratoconus (KC) is a disease characterized by limited corneal cone-like
protrusions accompanied by thinning of the corneal stroma in the area of protrusion,
which commonly occurs before and after puberty, manifests itself bilaterally, and is a …
protrusions accompanied by thinning of the corneal stroma in the area of protrusion,
which commonly occurs before and after puberty, manifests itself bilaterally, and is a …
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Diagnostic efficiency evaluation of visualized corneal biomechanical analysis combined with Pentacam on different stages of keratoconus
LI Dong, X Sheng - International Eye Science, 2024
… related-index in the diagnosis of subclinical keratoconus and forme fruste
keratoconus, and to provide evidence for early screening and diagnosis of
keratoconus.METHODS: A total of 65 patients(128 eyes)with keratoconus in Ningxia …
keratoconus, and to provide evidence for early screening and diagnosis of
keratoconus.METHODS: A total of 65 patients(128 eyes)with keratoconus in Ningxia …
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SCREENING FOR KERATOCONUS IN THE EARLY STAGES OF THE DISEASE
MQ Mamasoli o'g'li, NZ Isomiddinovna, AF Odilovich - TADQIQOTLAR, 2024
… Keratoconus is a progressive, degenerative disorder of the cornea characterized
by thinning … This article reviews the methods of screening for keratoconus in its
early stages, emphasizing … improve clinical outcomes and reduce the burden of …
by thinning … This article reviews the methods of screening for keratoconus in its
early stages, emphasizing … improve clinical outcomes and reduce the burden of …
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[PDF] A hybrid Transformers-based convolutional neural network model for keratoconus detection in Scheimpflug-based dynamic corneal deformation videos
H Abdelmotaal, R Hazarbasanov, R Salouti… - 2024
… We retrospectively analyzed datasets with records of 821 nonconsecutive, refractive
surgery candidates, and patients with unilateral or bilateral keratoconus, in these two
centers located on two different continents, which ensured the ethnic diversity of …
surgery candidates, and patients with unilateral or bilateral keratoconus, in these two
centers located on two different continents, which ensured the ethnic diversity of …
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Incidence and presenting clinical features of pediatric keratoconus in a US population
MK Farazdaghi, ED Bothun, M Tran, DO Hodge… - Journal of American …, 2024
… with keratoconus while residing in Olmsted County, Minnesota, from January 1,
1975, through December 31, 2019, were retrospectively reviewed. The records of
patients <19 years with keratoconus … <19 years of age diagnosed with …
1975, through December 31, 2019, were retrospectively reviewed. The records of
patients <19 years with keratoconus … <19 years of age diagnosed with …
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Visual, topographic, and refractive outcomes of the implantation of asymmetric segments of the intrastromal corneal ring in keratoconus.
ER Diniz, AS Moriyama, JCB Torres, ACI Horita… - Revista Brasileira de …, 2024
Objetivo: Avaliar os resultados visuais, topográficos e refrativos do implante de
segmentos assimétricos (AS) de anel intracorneano (ICRS) em olhos com
ceratocone e astigmatismo irregular/assimétrico (fenótipos tipo 2 Duck e 3 …
segmentos assimétricos (AS) de anel intracorneano (ICRS) em olhos com
ceratocone e astigmatismo irregular/assimétrico (fenótipos tipo 2 Duck e 3 …
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[PDF] Corneal densitometry changes post-CXL for keratoconus: Comparative evaluation of epithelium-off, contact lens-assisted, and transepithelial techniques
B Gupta, C Malhotra, S Dhar, K Abhyapal, AK Jain… - Indian Journal of …, 2024
… Purpose: To evaluate changes in corneal backscattering after collagen cross‑linking
(CXL) for progressive keratoconus and compare its course with different techniques
– standard epithelium‑off CXL (SCXL), contact lens‑assisted CXL (CACXL), and …
(CXL) for progressive keratoconus and compare its course with different techniques
– standard epithelium‑off CXL (SCXL), contact lens‑assisted CXL (CACXL), and …
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[PDF] Misclassification of Eyes With Progressive Keratoconus Using the KISA% Index
B Hammoud, WJ Dupps Jr, G Scarcelli, JB Randleman - Journal of Refractive Surgery, 2024
… This was a retrospective case-control study of consecutive patients with confirmed
progressive keratoconus and a contemporaneous … KISA% index and inferior-superior
(IS) values were obtained from the Pentacam topometric/keratoconus staging map …
progressive keratoconus and a contemporaneous … KISA% index and inferior-superior
(IS) values were obtained from the Pentacam topometric/keratoconus staging map …
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[PDF] Comparing the Postoperative Outcomes of Intrastromal Corneal Ring Segments in Three Different Topographic Patterns of Eccentric Keratoconus
MO Yousif, RS Elkitkat, A Elmassry, MN Hamza… - Journal of Refractive …, 2024
… The study included patients with keratoconus who had implantation of
KERATACx ring segments. Three groups were segregated based on topographic
keratoconus patterns using the Sirius CSO Topographer (CSO Italia): type I ectasia …
KERATACx ring segments. Three groups were segregated based on topographic
keratoconus patterns using the Sirius CSO Topographer (CSO Italia): type I ectasia …
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Meibomian Gland Alterations in Keratoconus Patients After Corneal Cross-Linking
G Özkan, S Akkaya Turhan - Beyoglu Eye Journal
OBJECTIVES: To evaluate the changes in the meibomian glands (MGs) and ocular
surface parameters after corneal cross-linking (CXL) in keratoconus patients.
METHODS: Forty-eight eyes of 48 keratoconus patients that underwent epi-off CXL …
surface parameters after corneal cross-linking (CXL) in keratoconus patients.
METHODS: Forty-eight eyes of 48 keratoconus patients that underwent epi-off CXL …
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[HTML] Scleral lens surface crazing in an eye with giant papillary conjunctivitis and keratoconus: Outcome of lens surface polishing
S Sadhu, A Iqbal, B Srinivasan, P Padmanabhan - Journal of Clinical Ophthalmology …, 2024… in a patient with keratoconus (KC) and chronic giant papillary conjunctivitis (GPC).
A 45-year-old Asian male with known keratoconus (KC) … Scleral lenses are widely
used in the management of patients with keratoconus (KC) and various ocular …
A 45-year-old Asian male with known keratoconus (KC) … Scleral lenses are widely
used in the management of patients with keratoconus (KC) and various ocular …
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Quantifying Choroidal and Retinal Thicknesses Variations via Optical Coherence Tomography in Different Stages of Pediatric Keratoconus
N Masihpour, M Feghhi, MRP Bazaz, AM Rad… - 2024Purpose: Keratoconus (KCN) is characterized by corneal thinning and bulging,
leading to vision impairment. Assessing choroidal thickness (CT) in pediatric KCN (pKCN)
patients can provide insights for better understanding and managing the disease …
leading to vision impairment. Assessing choroidal thickness (CT) in pediatric KCN (pKCN)
patients can provide insights for better understanding and managing the disease …
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[PDF] Intraocular Pressure Measurements After Corneal Collagen Crosslinking With Riboflavin and Ultraviolet A in Eyes with Keratoconus
S Mahmud, SA Robin, NM Khan, L Khabir…… For the treatment of corneal ectasias such as keratoconus, corneal collagen cross-linking
(CXL) using … In this study, 31 eyes from 30 patients receiving CXL treatment
because to keratoconus were … In eyes with keratoconus, riboflavin-UVA CXL …
(CXL) using … In this study, 31 eyes from 30 patients receiving CXL treatment
because to keratoconus were … In eyes with keratoconus, riboflavin-UVA CXL …
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Customized Corneal Cross-Linking with Microneedle-Mediated Riboflavin Delivery for Keratoconus Treatment
M Yang, H Pan, T Chen, X Chen, R Ning, Q Ye, A Chen… - Advanced materials (Deerfield …In this study, a novel customized corneal cross-linking (CXL) treatment is explored
that utilizes microneedles (MNs) for targeted riboflavin (RF) administration prior to
the CXL procedure. Unlike the conventional "one-size-fits-all" approach, this …
that utilizes microneedles (MNs) for targeted riboflavin (RF) administration prior to
the CXL procedure. Unlike the conventional "one-size-fits-all" approach, this …
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[HTML] Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study
Y Chang, T Huang, S Yang, Y Li, D Chen - Translational Vision Science & …, 2024
Purpose: Although many studies have indicated that atopic dermatitis (AD) could
contribute to the risk of keratoconus (KC), the causality between AD and KC remains
controversial. This study aimed to explore the potential causal associations between …
contribute to the risk of keratoconus (KC), the causality between AD and KC remains
controversial. This study aimed to explore the potential causal associations between …
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Refractive reconstruction of keratoconus
J Zhang, J Hou, Y Dong, Y Lei - International Eye Science, 2024
Keratoconus is a progressive disease that seriously affects the eyesight of young
people. Keratoconus often causes high myopia, irregular astigmatism, and some
patients with advanced corneal scar, visual acuity significantly decreased. In the …
people. Keratoconus often causes high myopia, irregular astigmatism, and some
patients with advanced corneal scar, visual acuity significantly decreased. In the …
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Advances in the mechanisms of keratoconus secondary to vernal keratoconjunctivitis
Q Luo, C Zhang - International Eye Science, 2024
… Keratoconus is a corneal disease characterized by a local cone-like corneal
deformation. … mechanisms of vernal keratoconjunctivitis and keratoconus and the
progressive risk factors, … keratoconus, so as to provide reference for the …
deformation. … mechanisms of vernal keratoconjunctivitis and keratoconus and the
progressive risk factors, … keratoconus, so as to provide reference for the …
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Application progress of artificial intelligence in keratoconus
Y Zhou, Q Zeng - International Eye Science, 2024
… Abstract: Keratoconus is a blinding corneal … in keratoconus, Artificial intelligence(AI)mainly
involves early screening and diagnosis, severity grading, progression prediction,
and outcomes prediction. In this paper, the main applications and research progress …
involves early screening and diagnosis, severity grading, progression prediction,
and outcomes prediction. In this paper, the main applications and research progress …
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Ocular surface changes in keratoconus after long-term wearing of rigid gas permeable contact lens
N Zhang, M Qian, L Yang, J Yang - International Eye Science, 2024
… A total of 113 keratoconus patients(213 eyes)fitted with RGPCL in the optometry
center of Gansu Provincial … of keratoconus, including 42 cases(80 eyes)in mild
keratoconus group, 54 cases(102 eyes)in moderate keratoconus group and 17 …
center of Gansu Provincial … of keratoconus, including 42 cases(80 eyes)in mild
keratoconus group, 54 cases(102 eyes)in moderate keratoconus group and 17 …
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Accelerated corneal cross-linking with application of isotonic riboflavin under pedicled corneal epithelial flap for thin keratoconus
L Guo, C Zhou - International Eye Science, 2024
… keratoconus (corneal thickness less than 400 μm after epithelial removal).
METHODS: Retrospective study. A total of 46 patients (74 eyes) with keratoconus …
feasible for patients with thin keratoconus, achieving similar control of keratoconus …
METHODS: Retrospective study. A total of 46 patients (74 eyes) with keratoconus …
feasible for patients with thin keratoconus, achieving similar control of keratoconus …
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[PDF] A Performance Evaluation of Large Language Model in Keratoconus: A Comparative Study of ChatGPT-3.5, ChatGPT-4.0, Gemini, Copilot, Chatsonic, and Perplexity
AH REYHAN, Ç MUTAF, U İrfan, F YÜKSEKYAYLA - 2024
Abstract Background: This study evaluates the ability of six popular chatbots;
ChatGPT-3.5, ChatGPT-4.0, Gemini, Copilot, Chatsonic, and Perplexity to provide
reliable answers to questions concerning keratoconus. Methods: Chatbots …
ChatGPT-3.5, ChatGPT-4.0, Gemini, Copilot, Chatsonic, and Perplexity to provide
reliable answers to questions concerning keratoconus. Methods: Chatbots …
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Clinical study on the difference of binocular biological parameters of the anterior segment in early diagnosis of keratoconus
YE Fan, J Xue - International Eye Science, 2024
AIM: To investigate the diagnostic value of the difference of binocular biological
parameters of the anterior segment in early keratoconus. METHODS: Retrospective
case-control study. A total of 183 patients (366 eyes) who visited our hospital from …
parameters of the anterior segment in early keratoconus. METHODS: Retrospective
case-control study. A total of 183 patients (366 eyes) who visited our hospital from …
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[HTML] A genetic investigation in five Chinese families with keratoconus
Q Lin, X Wang, X Peng, T Han, L Sun, X Zhang, X Zhou - PeerJ, 2024
Methods In the five families affected by KC, medical records, clinical observations,
and blood samples were collected from all individuals. All KC family members (n= 20)
underwent both whole exome sequencing of genomic DNA and Sanger sequencing …
and blood samples were collected from all individuals. All KC family members (n= 20)
underwent both whole exome sequencing of genomic DNA and Sanger sequencing …
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[HTML] Comparison of Pentacam data in patients with diagnostic criteria for keratoconus in only one eye
KA Carvalho, NAE Oliveira, RS Melice, RHMM Rocha… - Revista Brasileira de …, 2024
… This study reviewed charts of patients with keratoconus in one eye and forme
fruste keratoconus (FFKC) in the other, from January to December … Twenty-two
eyes of 11 patients were compared, and only one eye had established diagnostic …
fruste keratoconus (FFKC) in the other, from January to December … Twenty-two
eyes of 11 patients were compared, and only one eye had established diagnostic …
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Keratoconus: Optical and Surgical Management
M Mohammadpour, M Khorrami-Nejad - 2024
This is an updated and comprehensive treatise on optical, medical, and surgical
management of keratoconus with an exclusive panoramic view of all existing
modalities for confronting this serious disabling morbidity affecting people in their …
management of keratoconus with an exclusive panoramic view of all existing
modalities for confronting this serious disabling morbidity affecting people in their …
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Intra-Operative and Post-Operative Suture-Related Considerations and Complications of Corneal Graft for Keratoconus
A Peyman, A Aslani, M Pourazizi - Keratoconus, 2025
Corneal grafting, specifically penetrating keratoplasty (PK) and deep anterior
lamellar keratoplasty (DALK), are commonly used surgical interventions for
advanced keratoconus and corneal opacities. This chapter will review the …
lamellar keratoplasty (DALK), are commonly used surgical interventions for
advanced keratoconus and corneal opacities. This chapter will review the …
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Keratoconus Classification
M Ghoreishi, A Eslampoor - Keratoconus
… In the past, the path to keratoconus management was mainly limited to the
advanced forms of the disease with typical clinical findings (… This chapter reviews
different classification systems currently available for assessing keratoconus severity …
advanced forms of the disease with typical clinical findings (… This chapter reviews
different classification systems currently available for assessing keratoconus severity …
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Keratoconus Definition, Epidemiology, and Risk Factors
L Ghiasian - Keratoconus, 2025
… Most experts admit that a real unilateral keratoconus does not exist. Multiple
hypotheses have been proposed, including genetics, … may affect unknown
pathophysiology of the keratoconus.8 Despite many studies, the enigmatic …
hypotheses have been proposed, including genetics, … may affect unknown
pathophysiology of the keratoconus.8 Despite many studies, the enigmatic …
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New International Achievements in Modern Modalities of Keratoconus Treatment
K Jadidi, SA Mosavi - Keratoconus, 2024
… disorders such as keratoconus but can rarely be used for severe keratoconus, 7
and is not a solution for all keratoconus cases. According … development of new
devices and methods can provide further help in treating keratoconus on a wider …
and is not a solution for all keratoconus cases. According … development of new
devices and methods can provide further help in treating keratoconus on a wider …
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Complete 360-Degree Intrastromal Corneal Rings with and without Corneal Cross-Linking in the Management of Keratoconus
M Khorrami-Nejad, M Mohammadpour, R Abulhosein - Keratoconus, 2024
An effective therapeutic option for individuals with keratoconus (KCN) is the
intrastromal corneal ring (ICR), a type of implant that is either segmental arc-shaped
or 360-degree annular-shaped. 1 , 2 ICRs were initially designed by Barraquer (1949) …
intrastromal corneal ring (ICR), a type of implant that is either segmental arc-shaped
or 360-degree annular-shaped. 1 , 2 ICRs were initially designed by Barraquer (1949) …
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Management of Keratoconus with Contact Lenses
M Khorrami-Nejad, YA Shakor - Keratoconus, 2025
Keratoconus (KCN) is a type of corneal disease that does not involve inflammation
but is characterized by the protrusion of a cone-shaped area and gradual thinning of
the cornea.1–3 The thinnest location is usually found at the corneal apex, which is …
but is characterized by the protrusion of a cone-shaped area and gradual thinning of
the cornea.1–3 The thinnest location is usually found at the corneal apex, which is …
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Ocular Surface Considerations in Corneal Transplantation in Keratoconus
S Zarei-Ghanavati, MM Shariati - Keratoconus, 2025
Keratoconus (KC) is an asymmetric bilateral ocular disease, characterized by
progressive corneal thinning and steepening. 1 Changes in the curvature and
thickness of the cornea cause irregular astigmatism and visual impairment …
progressive corneal thinning and steepening. 1 Changes in the curvature and
thickness of the cornea cause irregular astigmatism and visual impairment …
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[HTML] Pulsed corneal crosslinking in the treatment of Keratoconus: a systematic review and meta-analysis
M Qureshi, SL Watson, H Kandel - Graefe's Archive for Clinical and Experimental …, 2024
… into P-CXL as an emerging option in the treatment of progressive keratoconus.
The primary objective of this systematic review was to investigate the effectiveness
of P-CXL in treating keratoconus and to determine whether it exhibits superior …
The primary objective of this systematic review was to investigate the effectiveness
of P-CXL in treating keratoconus and to determine whether it exhibits superior …
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[HTML] Implantable collamer lens for visual rehabilitation in keratoconus-a narrative review of visual and refractive outcomes
R Fairaq, HB Helayel, H Abdulhadi, SM Almuwarraee… - JFO Open Ophthalmology, 2024
… Keratoconus (KC) is a progressive corneal degeneration characterized by … in
keratoconus and the timing between ICL implantation and corneal crosslinking and/or
intrastromal corneal ring segment procedures. Additionally, we review challenges …
keratoconus and the timing between ICL implantation and corneal crosslinking and/or
intrastromal corneal ring segment procedures. Additionally, we review challenges …
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Vision Improvement in Keratoconus Patients Trained with Perceptual Learning: A Randomized Controlled Trial
XH Tang, MY Wang, JY Jiang, FQ Zhou, D Li, SS Chen… - American Journal of …, 2024
Background Keratoconus (KC) is a corneal ectasia disease in which the vision of
some patients cannot achieve satisfaction by spectacle corrections. However, not
everyone can embrace contact lenses to achieve better vision. Perceptual learning (PL) …
some patients cannot achieve satisfaction by spectacle corrections. However, not
everyone can embrace contact lenses to achieve better vision. Perceptual learning (PL) …
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Managing A Middle-aged Patient with Bilateral Neglected Keratoconus: A Rare Case Report
PA Universade, C Aritonang - International journal of health sciences
… and being noncontact for keratoconus screening. However, several developing
countries have delayed keratoconus management due to … Here we report a case
of underdiagnosed and mistreated by high astigmatism, leading to a neglected case …
countries have delayed keratoconus management due to … Here we report a case
of underdiagnosed and mistreated by high astigmatism, leading to a neglected case …
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Deep Anterior Lamellar Keratoplasty in Keratoconus
B Dave, D Patel, J Bavishi, V Hadvani - International journal of health sciences
… keratoconus in terms of best corrected and uncorrected visual acuity, average K
and topographic astigmatism. Settings and design: Prospective interventional case
series study Material and methods: 28 eyes of 28 patients diagnosed with …
and topographic astigmatism. Settings and design: Prospective interventional case
series study Material and methods: 28 eyes of 28 patients diagnosed with …
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Tomographic and topographic predictive factors of big bubble formation during deep anterior lamellar keratoplasty in keratoconus
L Lucchino, G Visioli, F Scarinci, RAMC Gisoldi… - British Journal of …, 2024
… Big bubble (BB) formation in deep anterior lamellar keratoplasty for keratoconus (KC)
can be influenced by surgical technique and corneal … . Influence of graft-host
interface on the quality of vision after deep anterior lamellar keratoplasty in patients …
can be influenced by surgical technique and corneal … . Influence of graft-host
interface on the quality of vision after deep anterior lamellar keratoplasty in patients …
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Big bubble formation in deep anterior lamellar keratoplasty may be more successful in early keratoconus eyes
HS Son, U Soiberman - British Journal of Ophthalmology, 2024
… The study provides topographic evidence for a higher BB success rate among
earlier stages of keratoconus, as … early keratoconus eyes with no tomographic
signs of posterior stromal scars.1 The authors postulate that the significant corneal …
earlier stages of keratoconus, as … early keratoconus eyes with no tomographic
signs of posterior stromal scars.1 The authors postulate that the significant corneal …
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[PDF] Assessment of OCT and Angio-OCT Parameters in Keratoconus Patients with and without Penetrating Keratoplasty
AM Gadamer, P Miklaszewski, D Janiszewska-Bil… - J. Clin. Med, 2024
… in keratoconus patients after penetrating keratoplasty, highlighting RPCs inside
the disc as a potential diagnostic tool for further assessment of keratoconus. … This
study evaluated the RPCs in keratoconus patients with and without PKP using OCT …
the disc as a potential diagnostic tool for further assessment of keratoconus. … This
study evaluated the RPCs in keratoconus patients with and without PKP using OCT …
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Macular choroidal thickness in keratoconus
A Abbasi Mehrabadi, J Sadeghi, N Shoeibi… - Clinical and Experimental …, 2024
… This study aimed to compare the difference in choroidal thickness between
keratoconus patients and two control groups of myopic-… A case-control study was
undertaken which included 50 patients with keratoconus, 50 with myopic-astigmatism …
keratoconus patients and two control groups of myopic-… A case-control study was
undertaken which included 50 patients with keratoconus, 50 with myopic-astigmatism …
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[HTML] Gene‒Environment Interaction Between CAST Gene and Eye-Rubbing in the Chinese Keratoconus Cohort Study: A Case-Only Study
S Yin, L Xu, K Yang, Q Fan, Y Gu, C Yin, Y Zang… - … Ophthalmology & Visual …, 2024
Purpose: Keratoconus (KC), characterized by progressive corneal protrusion and
thinning, is a complex disease influenced by the combination of genetic and
environmental factors. The purpose of this study was to explore potential gene‒environment …
thinning, is a complex disease influenced by the combination of genetic and
environmental factors. The purpose of this study was to explore potential gene‒environment …
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[HTML] Longitudinal assessment of the progression of severe keratoconus based on corneal topography
XD Yang, YR Wang, YY Liu, Y Lyu, WQ Wang - Scientific Reports, 2024
We aimed to assess long-term disease progression in patients with severe
keratoconus (KC). Clinical records of 125 patients (201 eyes) with severe KC
followed-up for > 12 months were retrospectively analyzed. From these, 28 patients (31 …
keratoconus (KC). Clinical records of 125 patients (201 eyes) with severe KC
followed-up for > 12 months were retrospectively analyzed. From these, 28 patients (31 …
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[HTML] Expression of matrix metalloproteinases and their inhibitors in corneal stromal fibroblasts and keratocytes from healthy and keratoconus corneas
T Berger, E Flockerzi, M Berger, N Chai, T Stachon… - Graefe's Archive for Clinical …, 2024
… (TIMP) in corneal stromal cells by distinguishing between fibroblasts and
keratocytes of healthy and keratoconus (KC) corneas. … Table 1 Descriptive data of
the keratoconus patients including the keratoconus ABCD grading system with the …
keratocytes of healthy and keratoconus (KC) corneas. … Table 1 Descriptive data of
the keratoconus patients including the keratoconus ABCD grading system with the …
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[PDF] Assessment of Corneal Cross-Linking Effect on Progressive Keratoconus by Using the ABCD Grading System
M Alzahrani, O Alammari, A Binyamin, R Alsulami… - Clinical Ophthalmology, 2024
Purpose The aim of this study was to assess changes in corneal parameters 6
months after corneal cross-linking for progressive keratoconus, using the ABCD
system. Patients and Methods This retrospective study was conducted at the King …
months after corneal cross-linking for progressive keratoconus, using the ABCD
system. Patients and Methods This retrospective study was conducted at the King …
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[PDF] Comparative Performance Analysis of Transformer-Based Pre-Trained Models for Detecting Keratoconus Disease
N Ahmed, MM Rahman, MF Ishrak, MIK Joy… - arXiv preprint arXiv …, 2024
… accurate and reliable keratoconus detection model. The study will also evaluate
the difficulties of differentiating keratoconus from other corneal … This research
compares different models to determine the best deep learning methods for …
the difficulties of differentiating keratoconus from other corneal … This research
compares different models to determine the best deep learning methods for …
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[PDF] Clinical Efficacy of Pocketing Air-Visco Expanding Detachment Deep Lamellar Keratoplasty for Keratoconus with Scars after Acute Hydrops
W Binghong, X Wenjia, Y Luyi, Z Yuanfang, Q Wenya - 2024
Background To analyze the clinical efficacy of PAVED (Pocketing Air-Visco
Expanding Detachment) deep anterior lamellar keratoplasty (DALK) for the
treatment of keratoconus with scarring after acute hydrops Methods 50 eyes from 50 …
Expanding Detachment) deep anterior lamellar keratoplasty (DALK) for the
treatment of keratoconus with scarring after acute hydrops Methods 50 eyes from 50 …
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Diagnostic ability of the corneal anterior and posterior surface area calculated by corneal modelling approach in early stage keratoconus patients
B Özelbaykal, O Kaya, B Kasım, T Birkandan, Y Koçluk - European Journal of …, 2024
… In this retrospective study, 116 eyes of 116 normal individuals and 366 eyes of
366 keratoconus patients were included. Keratoconus patients were divided into six
groups according to the topographic keratoconus classification of Pentacam …
366 keratoconus patients were included. Keratoconus patients were divided into six
groups according to the topographic keratoconus classification of Pentacam …
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Modeling biological growth of human keratoconus: On the effect of tissue degradation, location and size
B Fantaci, B Calvo, JF Rodríguez - Computers in biology and medicine
… keratoconus histopathology has been widely described in literature, its etiology is
still not clear. Being able to fully understand keratoconus … This work proposes a
novel continuum-based keratoconus growth model. The proposed framework …
still not clear. Being able to fully understand keratoconus … This work proposes a
novel continuum-based keratoconus growth model. The proposed framework …
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Risk factors for keratoconus in Pakistani population: A case control study
UG Khalid, A Zahid, F Akhtar, MA Ashraf, L ullah Khan - Rawal Medical Journal, 2024
… Controls were evaluated by an ophthalmologist and was declared as having no
signs of keratoconus. Controls was age and sex matched. … 30 were keratoconus
patients and 30 were general patients presenting Eye OPD. Data of 30 patients were …
signs of keratoconus. Controls was age and sex matched. … 30 were keratoconus
patients and 30 were general patients presenting Eye OPD. Data of 30 patients were …
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In silico characterization of the interaction of corneal tissue with a nitinol intracorneal implant for the treatment of keratoconus
A Patrissi - 2024
Keratoconus is a progressive bilateral and asymmetric eye disease of the cornea. It
causes progressive corneal thinning and a cone-… digital keratoconus cornea was
developed starting from a healthy 3D corneal model. The mechanical behaviour of …
causes progressive corneal thinning and a cone-… digital keratoconus cornea was
developed starting from a healthy 3D corneal model. The mechanical behaviour of …
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[HTML] … Automated Objective Measurements Acquired at the Preoperative Stage Estimate the Corrected Distance Visual Acuity after Corneal Cross-Linking in Keratoconus?
F Gilevska, A Biscevic, M Bohac, S Patel - Ophthalmology and Therapy, 2024
Introduction Objective markers describing corneal optical density (COD), thinnest
corneal thickness (TCT), and anterior (ARC) and posterior (PRC) surface radii over
the 3 mm thinnest region of the cornea were investigated to provide a model for …
corneal thickness (TCT), and anterior (ARC) and posterior (PRC) surface radii over
the 3 mm thinnest region of the cornea were investigated to provide a model for …
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Profile and Visual Outcome of Patients having Keratoconus Attending Tertiary Eye Hospital, Nepal
PR Adhikari, N Chaudhary, RR Karn - Journal of Nobel Medical College, 2024
… The aim of the study is to find out the clinical profile and visual outcome of the
patient having Keratoconus. … All the diagnosed Keratoconus patients referred from
cornea clinic to contact lens clinic for contact lens trial were included in this study …
patient having Keratoconus. … All the diagnosed Keratoconus patients referred from
cornea clinic to contact lens clinic for contact lens trial were included in this study …
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Evaluation of a new corneal scleral contact lens design in keratoconus
A Rotondi, C Stratta, M Frisani - Contact Lens and Anterior Eye, 2024
… keratoconus who are intolerant to RGP corneal CLs and unable to wear RGP
scleral CLs. Method: 23 eyes of 14 subjects (8 female, mean age 32, min 19 max 68
years) with keratoconus (… proven useful in visual rehabilitation in keratoconus and …
scleral CLs. Method: 23 eyes of 14 subjects (8 female, mean age 32, min 19 max 68
years) with keratoconus (… proven useful in visual rehabilitation in keratoconus and …
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[PDF] Comparative comparison of quality of life status of patients with myopia and keratoconus, Before and after surgery
N Ramezanghorbani, L Lotfi, N Morovati, N Morovati… - Koomesh, 2024
: Introduction: Visual impairment affects the quality of life of a person and endangers
his mental and social health and reduces his social activities and independence.
Therefore, clinical assessment of health-related quality of life in ocular patients is …
his mental and social health and reduces his social activities and independence.
Therefore, clinical assessment of health-related quality of life in ocular patients is …
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Long-term follow-up of repeated corneal cross-linking for progressive keratoconus in young patients
VGR Borges, LRS Stival, APA Nassaralla… - Rev. bras. oftalmol., 2024
… ) with progressive keratoconus underwent primary corneal cross-linking from
2009 to 2011. Despite the stability achieved with the epi-off corneal cross-linking,
keratoconus continued to progress after some time. Mean time to documented …
2009 to 2011. Despite the stability achieved with the epi-off corneal cross-linking,
keratoconus continued to progress after some time. Mean time to documented …
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[PDF] Evaluation of Macular and Choroidal Thickness in Patients with Subclinical Keratoconus
GD Arslan, D Özcan - COMPREHENSIVE MEDICINE
… in the tears of SKC and keratoconus eyes in patients diagnosed with unilateral
keratoconus supported the role of inflammation in the pathophysiology of
keratoconus.[13] Theories that claim a role for inflammation in the pathophysiology …
keratoconus supported the role of inflammation in the pathophysiology of
keratoconus.[13] Theories that claim a role for inflammation in the pathophysiology …
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Mendelian randomization analysis does not reveal a causal influence between keratoconus and three major mental disorders
X Zhang, Q Wang, F Cui, X Wu, C Zhang - Frontiers in Psychiatry
BackgroundObservational studies have suggested at a possible link between
keratoconus (KC) and various mental disorders, but the exact direction of causation
in these associations remains unclear. This study aims to investigate the potential …
keratoconus (KC) and various mental disorders, but the exact direction of causation
in these associations remains unclear. This study aims to investigate the potential …
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[HTML] Psychological and Psychiatric Characteristics of People with Keratoconus
S Florek, P Gościniewicz, M Suszka… - Reports, 2024
… with keratoconus is needed. The purpose of the present study was to determine
the links between the presence of keratoconus and … For the present study, an
exploratory hypothesis was developed that keratoconus patients are over-represented …
the links between the presence of keratoconus and … For the present study, an
exploratory hypothesis was developed that keratoconus patients are over-represented …
| | | |
[PDF] Efficacy of corneal collagen crosslinking procedure (C3-R) as a therapeutic modality in keratoconus patients
M Vyas
… Due to its advanced stage at diagnosis, paediatric keratoconus bears a higher
risk of severe visual impairment due to irregular astigmatism… Because of the
patients young age, keratoconus often has a significant negative effect on their …
risk of severe visual impairment due to irregular astigmatism… Because of the
patients young age, keratoconus often has a significant negative effect on their …
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[PDF] Evaluation of ophthalmic healthcare professional-led keratoconus management service in the United Kingdom
M Bourlaki, M Khan, S Bandyopadhyay, R Sahota… - 2024
… been established, including the setup of virtual keratoconus clinics and CXL
services led by … effectiveness and safety of OHP-led keratoconus service in
Birmingham and Midland Eye … We included 170 patients with suspected/confirmed …
services led by … effectiveness and safety of OHP-led keratoconus service in
Birmingham and Midland Eye … We included 170 patients with suspected/confirmed …
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… Photorefractive Keratectomy Combined with Accelerated Corneal Collagen Cross-linking versus Cross-Linking Alone for Progressive Keratoconus: A Long-Term …
Z Dai, Z Liu, Y Zhang, Y Yuan, Y Liu, Y Wang, S Yu… - Frontiers in Medicine
Purpose: To comprehensively compare the long-term outcome of the combined
topography guided photorefractive keratectomy (TG-PRK) with accelerated corneal
cross-linking (ACXL) and ACXL alone in eyes with progressive keratoconus. The …
topography guided photorefractive keratectomy (TG-PRK) with accelerated corneal
cross-linking (ACXL) and ACXL alone in eyes with progressive keratoconus. The …
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Performance Comparison of Machine Learning Algorithms for Keratoconus Detection
ZJ Muhsin, R Qahwaji, I Ghafir, M Al Bdour, S AlRyalat… - 2024 IEEE 30th …, 2024
This paper provides an in-depth examination of eight Machine Learning (ML)
algorithms commonly employed in diagnosing keratoconus (KC) over the past
decade. The analysis is conducted using a clinical dataset accumulated by the …
algorithms commonly employed in diagnosing keratoconus (KC) over the past
decade. The analysis is conducted using a clinical dataset accumulated by the …
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[HTML] OPPORTUNITIES FOR IMPROVING THE LONG-TERM MANAGEMENT OF KERATOCONUS PATIENTS
A Nau, C Nau, E Shorter, M Schornack, J Fogt… - Journal of Contact lens …, 2024
Background and Objective: This study determined whether practitioners specializing
in keratoconus (KC) adhere to published guidelines for disease management and to
what extent comorbid conditions of dry eye, contact lens tolerance, and …
in keratoconus (KC) adhere to published guidelines for disease management and to
what extent comorbid conditions of dry eye, contact lens tolerance, and …
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Cell Volume Regulation of Endothelial Cells Is Impaired in Keratoconus Cornea
IM Kuseina, LE Katkova, GS Baturina, IG Palchikova… - Biologičeskie membrany, 2024
… with keratoconus was investigated. The endothelial cells were obtained from
surgery material. Measurements of osmotic aqueous permeability (Pf) of endothelial
cells in normal and in keratoconus … in cell volume regulating mechanism in …
surgery material. Measurements of osmotic aqueous permeability (Pf) of endothelial
cells in normal and in keratoconus … in cell volume regulating mechanism in …
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[HTML] Triad of benign fleck retina with keratoconus with myopia–A rare case report
A Gupta, V Agrawal - Indian Journal of Ophthalmology-Case Reports, 2024
… keratoconus is quoted in the literature as fairly rare. [ 6 ] There also seemed to be
a link between the severity of the retinal degeneration and the frequency of the
keratoconus; the more severe cases appeared to be more prone to developing …
a link between the severity of the retinal degeneration and the frequency of the
keratoconus; the more severe cases appeared to be more prone to developing …
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[HTML] Tear meniscus particle analysis with anterior segment optical coherence tomography in keratoconus
SA Seyyar, Ş Büyükbayram, GG Soysal, S Ayla… - Indian Journal of …, 2024
… tear film in keratoconus patients, with higher TMT and lower POAP levels in the
keratoconus group compared to the healthy control group. … the tear meniscus in
keratoconus. The effect of increased inflammatory mediators in the tears of patients …
keratoconus group compared to the healthy control group. … the tear meniscus in
keratoconus. The effect of increased inflammatory mediators in the tears of patients …
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Correction: Evaluation of ophthalmic healthcare professional-led keratoconus management service in the United Kingdom: the Birmingham and Midland Eye Centre …
M Bourlaki, M Khan, S Bandyopadhyay, R Sahota… - Eye, 2024
The term "allied health professional (s)" was replaced with "ophthalmic healthcare
professional (s)" in the title and throughout the main text of this article. The
terminology "allied health professionals" refers to a distinct group of healthcare …
professional (s)" in the title and throughout the main text of this article. The
terminology "allied health professionals" refers to a distinct group of healthcare …
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[PDF] Femtosecond Laser Assisted Deep Anterior Lamellar Keratoplasty versus Manual Technique for Treatment of Keratoconus
A Nooreldin, AMG EL-Kareem - The Egyptian Journal of Hospital Medicine (July 2024)
Background: DALK is agolden method for treatment of keratoconus with
preservation of endothelium. femtosecond laser-assisted DALK (F-DALK) is a new
technique used nowadays to overcome difficulties of an old one. Aims: To contrast …
preservation of endothelium. femtosecond laser-assisted DALK (F-DALK) is a new
technique used nowadays to overcome difficulties of an old one. Aims: To contrast …
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[HTML] Inflammation and keratoconus: A comprehensive bidirectional Mendelian randomization analysis
X Zhang, F Cui, Q Wang, C Zhang - Medicine, 2024
An increasing body of evidence supports the involvement of inflammation and
immune responses in the occurrence and development of keratoconus (KC).
However, the causal relationship between inflammatory factors and KC remains …
immune responses in the occurrence and development of keratoconus (KC).
However, the causal relationship between inflammatory factors and KC remains …
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Comparisons of corneal biomechanical and higher-order aberrations between thin normal cornea and Forme Fruste keratoconus
M Liu, X Liu, X Liu, T Chen, C Liu, G Tian - 2024
… keratoconus of the contralateral eye [9] . By improving the diagnostic rate of
identifying potentially high-risk corneas or early keratoconus, … It has been shown [11]
that changes in the biomechanical characteristics of keratoconus may precede …
identifying potentially high-risk corneas or early keratoconus, … It has been shown [11]
that changes in the biomechanical characteristics of keratoconus may precede …
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[HTML] Impacts of keratoconus on quality of life: a qualitative study
L Fan, H Kandel, SL Watson - Eye, 2024
… reported in this study on patients receiving a single type of treatment for their
keratoconus [15]. Knowledge of the patient experience of … QoL impacts of
keratoconus in the real-world, this study aimed to evaluate the patient experience of …
keratoconus [15]. Knowledge of the patient experience of … QoL impacts of
keratoconus in the real-world, this study aimed to evaluate the patient experience of …
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Repeatability and agreement of two ocular biometers with single and dual Scheimpflug cameras in keratoconus eyes
C Lwowski, D Krüger, T Kohnen - Graefe's Archive for Clinical and Experimental …, 2024
Background To evaluate the repeatability and agreement of two different ocular
biometers and Scheimpflug devices in keratoconus eyes. Methods This prospective,
comparative trial took place at the University hospital, Goethe University, Frankfurt …
biometers and Scheimpflug devices in keratoconus eyes. Methods This prospective,
comparative trial took place at the University hospital, Goethe University, Frankfurt …
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Comparison of a Scheimpflug device and a spectral domain optical coherence tomography device for keratoconus detection/Author Honeder Andreas
A Honeder - 2024
… our keratoconus outpatient clinic in a retrospective fashion. In all cases, a
Scheimpflug measurement (Pentacam HR, Oculus, Germany) and a spectral domain
OCT (MS-39, CSI, Italy) was available. A detailed comparison including standard …
Scheimpflug measurement (Pentacam HR, Oculus, Germany) and a spectral domain
OCT (MS-39, CSI, Italy) was available. A detailed comparison including standard …
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[HTML] Detecting early changes in choroidal vascularity and thickness using optical coherence tomography in patients with corneal crosslinking for keratoconus
S Doganay, MO Kiristioglu, D Doganay, E Kacmaz - International Journal of …, 2024
AIM To investigate changes in choroidal thickness and vascularity in keratoconus
patients treated with corneal crosslinking. METHODS This study evaluated 28 eyes
of 22 patients with keratoconus who underwent corneal crosslinking. The choroidal …
patients treated with corneal crosslinking. METHODS This study evaluated 28 eyes
of 22 patients with keratoconus who underwent corneal crosslinking. The choroidal …
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[HTML] Improved Feature Fusion and Representation for Detecting Keratoconus from Corneal Maps
RM Hazarbassanov, L Al-Zubaidi, A Al-Timemy, C Arce… - … Ophthalmology & Visual …, 2024
Purpose: This study aims to develop and validate a hybrid model that integrates
deep learning, specifically feature fusion, for the detection of keratoconus (KC) using
corneal maps collected from a dual Scheimpflug analyzer. Methods: We collected …
deep learning, specifically feature fusion, for the detection of keratoconus (KC) using
corneal maps collected from a dual Scheimpflug analyzer. Methods: We collected …
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[HTML] Diagnosis of forme fruste keratoconus with scheimpflug photography in Ghanaian patients
S Lartey, E Appiagyei - BMC Ophthalmology, 2024
… myopic astigmatism from forme fruste keratoconus using Pentacam parameters
and develop a predictive model for early keratoconus detection. … a crucial role in
predicting forme fruste keratoconus, emphasizing its relevance as an early indicator …
and develop a predictive model for early keratoconus detection. … a crucial role in
predicting forme fruste keratoconus, emphasizing its relevance as an early indicator …
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Repeatability of Automatic Measurements by an Anterior Segment Swept-Source OCT Biometer in Patients With Keratoconus
I Abicca, D Schiano-Lomoriello, M Gilardi, D Giannini… - Journal of Refractive …, 2024
… The purpose of the current study was to investigate the repeatability of automatic
measurements by the ANTERION in eyes with keratoconus … III keratoconus
included in our study population. In the future, a larger number of eyes for each …
measurements by the ANTERION in eyes with keratoconus … III keratoconus
included in our study population. In the future, a larger number of eyes for each …
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[PDF] Progressive Keratoconus Treatment with Transepithelial 2-Step Phototherapeutic Keratectomy Combined with Corneal Cross-Linking (CXL): Clinical Outcomes and …
AJ Kanellopoulos, AJ Kanellopoulos - 2024
… , combined with higher fluence CXL in the effective management and visual
rehabilitation of progressive keratoconus. Methods: 17 cases with progressive
keratoconus were treated with a corneal surface excimer laser ablation …
rehabilitation of progressive keratoconus. Methods: 17 cases with progressive
keratoconus were treated with a corneal surface excimer laser ablation …
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[HTML] Elevating optometric keratoconus management
K Gilbert Spear - 2024
Disclaimer: The information in this article is provided for general informational
purposes only and may not reflect the current law in your jurisdiction. The
information contained in this article is not legal advice, and it is not intended to be a …
purposes only and may not reflect the current law in your jurisdiction. The
information contained in this article is not legal advice, and it is not intended to be a …
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[HTML] Inter-zonal epithelial thickness differences for early keratoconus detection using optical coherence tomography
T Naujokaitis, R Khoramnia, M Friedrich, HS Son… - Eye, 2024
… In conclusion, we found the inter-zonal ET differences to correlate with the
tomographical changes in keratoconus and to be increased not only in
tomographically significant keratoconus, but also in tomographically normal …
tomographical changes in keratoconus and to be increased not only in
tomographically significant keratoconus, but also in tomographically normal …
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[PDF] Clinical profile and outcomes of rejection after deep anterior lamellar keratoplasty in keratoconus
P Sudaboina, S Chaurasia, S Murthy - Indian Journal of Ophthalmology, 2024
… In this study, all six eyes with rejection had DALK performed for keratoconus. The
potential risk factors that were identified were vernal keratoconjunctivitis in four eyes
(Patient 1, 2, 3, and 4), lid margin disease in one eye (Patient 5), eccentric graft in …
potential risk factors that were identified were vernal keratoconjunctivitis in four eyes
(Patient 1, 2, 3, and 4), lid margin disease in one eye (Patient 5), eccentric graft in …
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[HTML] MEAN CHANGE IN ENDOTHELIAL CELL DENSITY AFTER COLLAGEN CROSS-LINKING IN PROGRESSIVE KERATOCONUS: A QUASI EXPERIMENTAL STUDY
S Khan, A Maqbool, A Gohar, U Arshad, R Sharif, S Zia - Gomal Journal of Medical …, 2024
Background: Corneal collagen cross-linking (CXL) is a minimally invasive technique
that halts the advancement of keratoconus. The objective of our study was to
determine mean change in endothelial cell density in patients with advancing …
that halts the advancement of keratoconus. The objective of our study was to
determine mean change in endothelial cell density in patients with advancing …
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[HTML] Smart decision support system for keratoconus severity staging using corneal curvature and thinnest pachymetry indices
ZJ Muhsin, R Qahwaji, M AlShawabkeh, SA AlRyalat… - Eye and Vision, 2024
This study proposes a decision support system created in collaboration with
machine learning experts and ophthalmologists for detecting keratoconus (KC)
severity. The system employs an ensemble machine model and minimal corneal …
machine learning experts and ophthalmologists for detecting keratoconus (KC)
severity. The system employs an ensemble machine model and minimal corneal …
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[PDF] Early findings in a randomised controlled trial on crosslinking protocols using isoosmolar and hypoosmolar riboflavin for the treatment of progressive keratoconus
I Gustafsson, T Olafsdotttir, O Neumann, P Johansson… - Acta Ophthalmologica, 2024
Purpose To present baseline characteristics and to present the perioperative
corneal thickness during corneal crosslinking (CXL) treatment for progressive
keratoconus and to describe how the addition of sterile water (SW) efficaciously can …
corneal thickness during corneal crosslinking (CXL) treatment for progressive
keratoconus and to describe how the addition of sterile water (SW) efficaciously can …
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Elevating keratoconus management.
KG Spear - Optometry Times, 2024
The article discusses the importance of professional practice guidelines in optometry,
specifically focusing on the diagnosis and management of keratoconus (KC). While
there are currently no professional society guidelines for KC in optometry, the …
specifically focusing on the diagnosis and management of keratoconus (KC). While
there are currently no professional society guidelines for KC in optometry, the …
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Changes in the precorneal tear film at various stages of keratoconus
VV Averich, IA Bubnova - Vestnik oftalmologii, 2024
The combination of keratoconus (KC) with signs of dry eye disease (DES) has been
described in numerous scientific publications. At the same time, there is a
relationship between KC stage and an increase in the severity of DES symptoms …
described in numerous scientific publications. At the same time, there is a
relationship between KC stage and an increase in the severity of DES symptoms …
| | | |
Changes in the precorneal tear film at various stages of keratoconus
VV Averich, IA Bubnova - Vestnik oftalmologii, 2024
The combination of keratoconus (KC) with signs of dry eye disease (DES) has been
described in numerous scientific publications. At the same time, there is a
relationship between KC stage and an increase in the severity of DES symptoms …
described in numerous scientific publications. At the same time, there is a
relationship between KC stage and an increase in the severity of DES symptoms …
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[HTML] IOL Power Calculation in Keratoconus
JX Kane - Intraocular Lens Calculations, 2024
… The challenges with keratoconus are the corneal power measurement issues, the
IOL formula calculation errors, and the difficulty in refraction. The different formulas
used in keratoconus cases are compared. The Kane keratoconus formula utilises …
IOL formula calculation errors, and the difficulty in refraction. The different formulas
used in keratoconus cases are compared. The Kane keratoconus formula utilises …
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[PDF] Strengthening keratoconus management systems in South African public sector facilities
PMW Nkoana, KP Mashige, VR Moodley - African Vision and Eye Health, 2024
Background: Provision of comprehensive eye care remains a challenge in low to
medium income countries including South Africa. The recent surge of keratoconus (KC)
is exacerbating this challenge especially in terms of the need for specialised …
medium income countries including South Africa. The recent surge of keratoconus (KC)
is exacerbating this challenge especially in terms of the need for specialised …
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Keratoconus Detection Using Machine Learning
R Sandhiya, NM Chakkravthi, DN Vignesh… - 2024 3rd International …, 2024
… keratoconus promptly and accurately to take the necessary action and stop the
condition from progressing. The goal of this study is to use artificial intelligence
principles and cuttingedge technologies to diagnose keratoconus … whether a …
condition from progressing. The goal of this study is to use artificial intelligence
principles and cuttingedge technologies to diagnose keratoconus … whether a …
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[PDF] A Retrospective Study on keratoconus patients living in the central division, Fiji, 2015–2019.
V Kumar
Purpose: To understand the severity of keratoconus patients living in the central
division of Fiji. Methods: A total of sixty patients who attended to private clinic in
Suva (Fiji) were reviewed. The severity of KCN was graded into three (3) groups …
division of Fiji. Methods: A total of sixty patients who attended to private clinic in
Suva (Fiji) were reviewed. The severity of KCN was graded into three (3) groups …
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[PDF] KeratoEL: Detection of keratoconus using corneal parameters with ensemble learning
PK Paul, A Hossan, SMA Ullah - Health Science Reports, 2024
… between 0 and 4, forme fruste keratoconus (or keratoconus-suspect) for values
between 5 and 29, and keratoconus for values of 30 or higher. This data set, which
used CASIA labels, includes 390 keratoconus cases, 796 forme-fruste keratoconus …
between 5 and 29, and keratoconus for values of 30 or higher. This data set, which
used CASIA labels, includes 390 keratoconus cases, 796 forme-fruste keratoconus …
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Keratoconus: imaging modalities and management
N Alqudah - Medical hypothesis discovery and innovation in …, 2024
… for the online search: keratoconus, diagnosis of keratoconus, advances in the
diagnosis of keratoconus, topography or tomography, … keratoconus, advances in
the treatment of keratoconus, collagen crosslinking, intrastromal ring, keratoplasty …
diagnosis of keratoconus, topography or tomography, … keratoconus, advances in
the treatment of keratoconus, collagen crosslinking, intrastromal ring, keratoplasty …
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Keratoconus and Inflammatory bowel disease: Mendelian randomization
Y Jin, Y Wang, X Qiu, J Liu, S Qu - Frontiers in Genetics
… Studies have shown that inflammation may play a role in keratoconus.
Inflammatory enteritis (IBD), including ulcerative colitis(UC), is a … and keratoconus.
Methods The instrumental variable of IBD and UC was selected, the information of …
Inflammatory enteritis (IBD), including ulcerative colitis(UC), is a … and keratoconus.
Methods The instrumental variable of IBD and UC was selected, the information of …
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Exploring the Causal Relationship between BMI and Keratoconus: A Mendelian Randomization Study
J Wang, F Liu, J Mo, F Zheng, D Gong, J Su, S Ding… - Frontiers in Medicine
Background: Despite reports suggesting a link between obesity and keratoconus,
the causal relationship is not fully understood.We used genome-wide association
study (GWAS) data from public databases for a two-sample Mendelian …
the causal relationship is not fully understood.We used genome-wide association
study (GWAS) data from public databases for a two-sample Mendelian …
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Corneal densitometry changes after femtosecond laser-assisted intracorneal ring segments implantation in keratoconus
A Mounir, EM Mostafa, I Amer, AA Abdelgbar… - … hypothesis discovery and …, 2024
Background: Intrastromal corneal ring segments are commonly implanted in the
corneas of eyes with mild-to-moderate keratoconus; however, changes in corneal
densitometry (CD) after implantation are a matter of debate in the current literature …
corneas of eyes with mild-to-moderate keratoconus; however, changes in corneal
densitometry (CD) after implantation are a matter of debate in the current literature …
| | | |
[PDF] … pain and epithelial healing time after corneal collagen cross-linking following Conventional versus laser Epithelial removal in females with progressive keratoconus
I Fathy
Background: Keratoconus (KC) is a non-inflammatory, bilateral condition
characterized by increasing corneal thinning & bulging due to its biomechanical
instability, it is one of the most common disorders that affect corneal transparency …
characterized by increasing corneal thinning & bulging due to its biomechanical
instability, it is one of the most common disorders that affect corneal transparency …
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Clinical outcomes of femtosecond laser-assisted corneal allogenic intrastromal ring segment (CAIRS) in the treatment of keratoconus
A Kirgiz, BK Atik, M Emul, M Taskapili - Clinical & experimental ophthalmology
Background To evaluate the results of corneal allogenic intrastromal ring segment (CAIRS)
implantation in keratoconus. Methods The medical records of patients with
keratoconus who underwent CAIRS implantation were reviewed. The CAIRS …
implantation in keratoconus. Methods The medical records of patients with
keratoconus who underwent CAIRS implantation were reviewed. The CAIRS …
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[HTML] Systemic and ocular associations of Keratoconus
BS Hefley, AA Ali, P Bhattacharya, J Hjortdal… - Expert Review of …, 2024
Introduction Keratoconus (KC) is the most prevalent corneal ectasia in the world and
its pathogenesis is influenced by both ocular and systemic factors. This review
explores the multifaceted associations between keratoconus and systemic health …
its pathogenesis is influenced by both ocular and systemic factors. This review
explores the multifaceted associations between keratoconus and systemic health …
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Efficacy and safety of corneal cross-linking in Keratoconus patients with corneal thickness less than 400 μm: A systematic review
F Mohammadi, M Daniell, M Mcguinness, MZ Mustafa… - … Ophthalmology & Visual …, 2024
Purpose: A minimum corneal thickness of 400 μm after epithelium removal has been
recommended for keratoconus (KC) patients undergoing conventional corneal
collagen cross-linking (CXL) to avoid endothelial cell damage, excluding patients …
recommended for keratoconus (KC) patients undergoing conventional corneal
collagen cross-linking (CXL) to avoid endothelial cell damage, excluding patients …
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[HTML] Safety of refractive surgery in patients diagnosed with keratoconus through biomechanical and tomographic properties by an artificial intelligence algorithm
JLD Hickman, GP Hernandez, F Velazquez-Valenzuela… - … Ophthalmology & Visual …, 2024
… Patients with keratoconus diagnosed solely by tomographic data were not
considered candidates for LASIK. Patients were followed for a … This study
suggests that although an increased TBI is diagnostic for keratoconus, it is not …
considered candidates for LASIK. Patients were followed for a … This study
suggests that although an increased TBI is diagnostic for keratoconus, it is not …
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Worldwide analysis of climate-related determinants of keratoconus
H Shabani, J De Ridder, A Asaad, MA Meester… - … Ophthalmology & Visual …, 2024
… -related variables on keratoconus prevalence. Methods : We systematically
reviewed studies about keratoconus prevalence and incidence in the … Finally, the
potential impact of these climate variables on keratoconus prevalence was …
reviewed studies about keratoconus prevalence and incidence in the … Finally, the
potential impact of these climate variables on keratoconus prevalence was …
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[HTML] The comparative efficacy and safety of hypotonic vs isotonic riboflavin for corneal cross-linking in'thick'keratoconic corneas: a Save Sight Keratoconus Registry study
SL Watson, A Gupta, RA Mills, JY Chen, L Sullivan… - … Ophthalmology & Visual …, 2024
… corneal thickness> 400 µm who had undergone epithelium-off CXL for
keratoconus and had follow-up data at 1-year met the inclusion … Hypotonic
riboflavin compared to isotonic riboflavin produced a greater change in visual acuity …
keratoconus and had follow-up data at 1-year met the inclusion … Hypotonic
riboflavin compared to isotonic riboflavin produced a greater change in visual acuity …
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The association between keratoconus and mental health: a Save Sight Keratoconus Registry study
H Kandel, E Durakovic, SJ Sitaula, SL Watson - Investigative Ophthalmology & Visual …, 2024
… keratoconus and mental health. The primary objective was to understand the
prevalence of mental health symptoms among individuals with keratoconus … the
prospective, web-based, international Save Sight Keratoconus Registry data …
prevalence of mental health symptoms among individuals with keratoconus … the
prospective, web-based, international Save Sight Keratoconus Registry data …
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Can we model keratoconus' growth?
B Fantaci, B Calvo, JFR Matas - Investigative Ophthalmology & Visual Science, 2024
Purpose: Keratoconus is a bilateral disease, characterized by steepening and
thinning of corneal tissue, which alters its mechanical properties. Etiology and
development of this pathology are still not clear, even if its histopathology has been …
thinning of corneal tissue, which alters its mechanical properties. Etiology and
development of this pathology are still not clear, even if its histopathology has been …
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Social Determinants of Health as Risk Factors for Keratoconus in the All of Us Database
C Tan, A Puran, R Talebi, F Yu, V Tseng, A Coleman - Investigative Ophthalmology & …, 2024
… factors for keratoconus have been established, the impact of social determinants
of health on the epidemiology and pathophysiology of keratoconus are not well
understood. This study investigated associations between education and annual …
of health on the epidemiology and pathophysiology of keratoconus are not well
understood. This study investigated associations between education and annual …
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Risk of Keratoconus in Patients with ADHD: A TriNetX Analysis
ZS Hussain, J Muayad, A Loya, T Siddiqui, A Lee - Investigative Ophthalmology & …, 2024
Purpose: Recent research has pointed to a possible connection between attention-deficit/hyperactivity
disorder (ADHD) and keratoconus. This study seeks to examine the presence of this
association within an international database. Methods: We performed a …
disorder (ADHD) and keratoconus. This study seeks to examine the presence of this
association within an international database. Methods: We performed a …
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Changing landscape of keratoconus management
L Charters - 2024
… stage 3 keratoconus in the 8-mm zone and stages 3 and 4 keratoconus in the 6-mm
zone. "Our study provides a large normative database of aberrations seen in
keratoconus," … "We also provide a reference range for corneal wavefront in …
zone. "Our study provides a large normative database of aberrations seen in
keratoconus," … "We also provide a reference range for corneal wavefront in …
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[HTML] Combined DSAEK With Cataract Surgery in a Patient With Fuchs Endothelial Corneal Dystrophy and Keratoconus After Corneal Crosslinking
DG Vakalopoulos, VF Diakonis, L Lalou, M Katsimpras… - Cornea Open, 2024
Purpose: To report a combined Descemet stripping automated endothelial
keratoplasty (DSAEK) with cataract surgery in a case of Fuchs endothelial corneal
dystrophy (FECD) and keratoconus after corneal crosslinking combined with …
keratoplasty (DSAEK) with cataract surgery in a case of Fuchs endothelial corneal
dystrophy (FECD) and keratoconus after corneal crosslinking combined with …
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Long-Term Results of Sterile Corneal Allograft Ring Segments Implantation in Keratoconus Treatment.
KP FFN, C Tanriverdi, ZY Karaca, KD Tran, A Kilic - Cornea, 2024
… This prospective study included 62 eyes of 49 patients with keratoconus who
underwent corneal allograft ring segments implantation at … This study
demonstrated that sterile corneal allograft ring segments implantation is a safe and …
underwent corneal allograft ring segments implantation at … This study
demonstrated that sterile corneal allograft ring segments implantation is a safe and …
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Whole-exome Sequencing Screening for Candidate Genes and Variants Associated with Primary Sporadic Keratoconus in Chinese Patients
C Song, L Li, C Liu, L Hu, J Bai, W Liang, L Zhao… - Experimental Eye Research, 2024
The pathogenesis of keratoconus (KC) is complex, and genetic factors play an
important role. The purpose of this study was to screen and analyse candidate
genes and variants in Chinese patients with primary sporadic KC. Whole-exome …
important role. The purpose of this study was to screen and analyse candidate
genes and variants in Chinese patients with primary sporadic KC. Whole-exome …
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Identification of hub genes and molecular pathways in keratoconus by integrating bioinformatics and literature mining at the RNA level
F Meng, S Ren - International Ophthalmology, 2024
Objective Keratoconus (KC) is a condition characterized by progressive corneal
steepening and thinning. However, its pathophysiological mechanism remains
vague. We mainly performed literature mining to extract bioinformatic and related …
steepening and thinning. However, its pathophysiological mechanism remains
vague. We mainly performed literature mining to extract bioinformatic and related …
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[HTML] Late-onset corneal edema after customized crosslinking for progressive keratoconus
MMS Vandevenne, TTJM Berendschot, N Visser… - American Journal of …, 2024
… We describe a patient after customized crosslinking (CXL) for progressive
keratoconus who developed corneal edema with spontaneous … A 24-year-old
male was referred to our clinic with forme fruste keratoconus in his right eye and …
keratoconus who developed corneal edema with spontaneous … A 24-year-old
male was referred to our clinic with forme fruste keratoconus in his right eye and …
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Evaluation and Diagnosis of Keratoconus and Pellucid Marginal Degeneration
MR Santhiago, YS Rabinowitz, JB Randleman - Corneal Cross-Linking, 2024
Keratoconus (KC) is a bilateral, progressive, ectatic disorder associated with
different degrees of corneal stroma impairment characterized by biomechanical
weakening of multifactorial etiology. 1 The presentation and progression is based on …
different degrees of corneal stroma impairment characterized by biomechanical
weakening of multifactorial etiology. 1 The presentation and progression is based on …
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[PDF] Feature Selection and Detection of Keratoconus Using Random Forest and Bagging
Z Muhsin, R Qahwaji, SA AlRyalat, M Al Bdour…
Development of an effective machine learning method for detecting keratoconus (KC)
from dozens of corneal topography data remains a challenge. This paper proposes
a machine learning model based on an ensemble Bagging technique and a …
from dozens of corneal topography data remains a challenge. This paper proposes
a machine learning model based on an ensemble Bagging technique and a …
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[HTML] Biomechanical changes following corneal crosslinking in keratoconus patients
E Felter, R Khoramnia, M Friedrich, HS Son… - Graefe's Archive for Clinical …, 2024
Purpose To evaluate the biomechanical and tomographic outcomes of keratoconus
patients up to four years after corneal crosslinking (CXL). Methods In this
longitudinal retrospective-prospective single-center case series, the preoperative …
patients up to four years after corneal crosslinking (CXL). Methods In this
longitudinal retrospective-prospective single-center case series, the preoperative …
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Coexisting Keratoconus
DD Koch - What I Say, 2024
… As you know, in addition to your cataract, you have a condition called keratoconus.
Keratoconus is a thinning of the cornea that causes the cornea to take on an
irregular shape. This irregular shape ranges from mild (having only minimal effect on …
Keratoconus is a thinning of the cornea that causes the cornea to take on an
irregular shape. This irregular shape ranges from mild (having only minimal effect on …
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[PDF] Cost-effectiveness of corneal collagen cross-linking for keratoconus in district general hospital settings in the United Kingdom
P Dervenis, N Dervenis, FC Lam - 2024
Purpose Keratoconus is a bilateral corneal ectasia occurring in adolescence or early
adulthood. Collagen crosslinking is being used as an option to halt disease
progression. However, still many district general hospitals lack the equipment of …
adulthood. Collagen crosslinking is being used as an option to halt disease
progression. However, still many district general hospitals lack the equipment of …
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[HTML] Evaluation of allied health professional-led keratoconus management service in the United Kingdom: the Birmingham and Midland Eye Centre (BMEC) study
M Bourlaki, M Khan, S Bandyopadhyay, R Sahota… - Eye, 2024
… keratoconus clinics and CXL services led by nurses and optometrists [collectively
known as allied health professionals (AHPs)] [4, 5]. This cross-sectional study aimed
to examine the effectiveness and safety of AHP-led keratoconus … keratoconus from …
known as allied health professionals (AHPs)] [4, 5]. This cross-sectional study aimed
to examine the effectiveness and safety of AHP-led keratoconus … keratoconus from …
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[HTML] Identification of Keratoconus-Related Phenotypes in Three Ppip5k2 Mouse Models
T Akoto, R Hadvina, S Jones, J Cai, H Yu, H McCord… - … Ophthalmology & Visual …, 2024
Purpose: It is necessary to establish a mouse model of keratoconus (KC) for
research and therapy. We aimed to determine corneal phenotypes in 3 Ppip5k2
mouse models. Methods: Central corneal thickness (CCT) was determined using …
research and therapy. We aimed to determine corneal phenotypes in 3 Ppip5k2
mouse models. Methods: Central corneal thickness (CCT) was determined using …
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[HTML] The Association of a Single Nucleotide Variant in COL5A1 to Early Onset Keratoconus and Pectus Excavatum—Convergence of Extracellular Matrix Pathologies
G Bryant, P Moore, M Sathyamoorthy - Medicina, 2024
… Decreased central corneal thickness is a hallmark of the condition, and numerous
genes have played a role in altering corneal thickness and the subsequent development
of keratoconus. Variants in the structural and regulatory genes of the extracellular matrix …
genes have played a role in altering corneal thickness and the subsequent development
of keratoconus. Variants in the structural and regulatory genes of the extracellular matrix …
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[HTML] Hunting Keratoconus
H Goyal, S CARRUBBA
Global detection of keratoconus in its earliest stages remains a challenge to our field.
However, increased adoption of corneal topography and, more recently, tomography
has improved detection rates at incipient stages, even when overt clinical findings …
However, increased adoption of corneal topography and, more recently, tomography
has improved detection rates at incipient stages, even when overt clinical findings …
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Effect of corneoscleral lenses on visual acuity and corneal parameters in patients with keratoconus
A ALI, K HALEH, R SAEED, MT SEYYED - International Eye Science, 2024
… In this prospective study, 43 cases(83 eyes)with keratoconus were included and
examined. A corneoscleral contact lens was fitted, and … , since there were no
clinical noticeable changes in the corneal parameters, this lenses can be used …
examined. A corneoscleral contact lens was fitted, and … , since there were no
clinical noticeable changes in the corneal parameters, this lenses can be used …
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Effect of Corneal Allogenic Intrastromal Ring Segment (CAIRS) Implantation Surgery in Patients With Keratoconus According to Prior Corneal Cross-linking Status
B Yucekul, C Tanriverdi, S Taneri, FFN Keskin Perk… - Journal of Refractive …, 2024
… RESULTS This study included 67 eyes of 47 patients with advanced keratoconus.
The median age was 27 years (range: 20 to 52 years) and 34 (72%) of the patients
were men. There were 30 eyes in the CXL group and 37 eyes in the non-CXL group. …
The median age was 27 years (range: 20 to 52 years) and 34 (72%) of the patients
were men. There were 30 eyes in the CXL group and 37 eyes in the non-CXL group. …
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Allergic rhinitis and keratoconus: a systematic review and meta-analysis
JE Lo, YH Huang, N Bhattacharyya, EA Moulton… - The Journal of Allergy and …, 2024
… AR and 144 keratoconus, (2) provided the number of patients with or without
keratoconus and the 145 number of patients with keratoconus diagnosed with or
without AR, and (3) provided 146 information on how patients were diagnosed with …
keratoconus and the 145 number of patients with keratoconus diagnosed with or
without AR, and (3) provided 146 information on how patients were diagnosed with …
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[HTML] New data reveals startingly high prevalence of keratoconus in pediatric patients
J Harthan - 2024
Keratoconus (KC) is a progressive, bilateral, asymmetric corneal ectasia that results
in central or paracentral corneal thinning and steepening. 1, 2 The loss of corneal
biomechanical strength along with progressive thinning and steepening leads to …
in central or paracentral corneal thinning and steepening. 1, 2 The loss of corneal
biomechanical strength along with progressive thinning and steepening leads to …
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[PDF] Structural Outcomes of Corneal Cross-Linking for Keratoconus
Y Statsenko, D Smetanina, R Voitetskii, GL Simiyu… - 2024
Background: Studies have tried to identify predictors of functional markers of
keratoconus progression, whereas structural outcomes of collagen cross-linking
have not been properly investigated. Objective: find and set up a combination of …
keratoconus progression, whereas structural outcomes of collagen cross-linking
have not been properly investigated. Objective: find and set up a combination of …
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[HTML] Keratoconus and Corneal Ectasia with Relatively Low Keratometry
LPG Esporcatte, MQ Salomão, BT Lopes, N Sena… - Ophthalmology and Therapy, 2024
… Cases with maximum mean zone 3 mm keratometry (Kmax zone mean 3 mm)
lower than 47.6 diopters (D) were considered as low-keratometry keratoconus, and
cases with Kmax zone mean 3 mm higher than 47.6 D were regarded as high-keratometry …
lower than 47.6 diopters (D) were considered as low-keratometry keratoconus, and
cases with Kmax zone mean 3 mm higher than 47.6 D were regarded as high-keratometry …
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[PDF] Corneal Surface Elevation and Thickness in Relation to the Fit of Rigid Contact Lenses in Keratoconus and After Corneal Cross-Linking
A Biscevic, M Ahmedbegovic-Pjano, S Grisevic… - Clinical Ophthalmology, 2024
… and patients' comfort ratings in keratoconus. Citation34 The current study found
this occurred in keratoconus and post-CXL cases. … with more advanced and
severe keratoconus, and required slightly smaller lenses compared with the non-CXL …
this occurred in keratoconus and post-CXL cases. … with more advanced and
severe keratoconus, and required slightly smaller lenses compared with the non-CXL …
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Bioinformatics analysis of signature genes related to cell death in keratoconus
J Liu, J Gao, S Xing, Y Yan, X Yan, Y Jing, X Li - Scientific reports, 2024
… However, the etiology mechanism of keratoconus is still unclear. This study aims
to identify the signature genes related to cell death in keratoconus and examine the
function of these genes. A dataset of keratoconus from the GEO database was …
to identify the signature genes related to cell death in keratoconus and examine the
function of these genes. A dataset of keratoconus from the GEO database was …
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Corneal Cross-linking for Progressive Keratoconus
T Koller, S Seiler, T Seiler - Corneal Cross-Linking. Farhad Hafezi, 2024
… reported about cross-linking for keratoconus at several meetings. Wollensak et
al3 presented the first prospective study on CXL in 23 eyes with a follow-up of one
year or longer. He reported stabilization and even regression of the keratoconus as …
al3 presented the first prospective study on CXL in 23 eyes with a follow-up of one
year or longer. He reported stabilization and even regression of the keratoconus as …
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[PDF] Symposium: Keratoconus Long-term results of cornea collagen cross-linking with riboflavin for keratoconus
V Agrawal - Indian Journal of Ophthalmology
… In the light of currently available data, we can thus say that CXL is a safe
procedure that is successful in arresting keratoconus. It is advisable to perform this
procedure in patients with progressive keratoconus. Younger patients tend to have a …
procedure that is successful in arresting keratoconus. It is advisable to perform this
procedure in patients with progressive keratoconus. Younger patients tend to have a …
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Crosslinking with UV-A and riboflavin in progressive keratoconus: From laboratory to clinical practice–developments over 25 years
F Raiskup, R Herber, J Lenk, LE Pillunat, E Spoerl - Progress in Retinal and Eye …, 2024
Abstract Changes in the biomechanical and biochemical properties of the human
cornea play an important role in the pathogenesis of ectatic diseases. A number of
conditions in primarily acquired (keratoconus or pellucid marginal degeneration) or …
cornea play an important role in the pathogenesis of ectatic diseases. A number of
conditions in primarily acquired (keratoconus or pellucid marginal degeneration) or …
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[PDF] Effect of Collagen Crosslinking on Quality of Life in Patients with Keratoconus
M Dickey, R Phadke, J Baca, J Thomas, C Pepper…
Although keratoconus is fairly prevalent, the underlying mechanisms for its cause
are still unknown. At the same time, it is still the leading cause for a corneal
transplant in the United States. One treatment, collagen cross-linking, is relatively …
are still unknown. At the same time, it is still the leading cause for a corneal
transplant in the United States. One treatment, collagen cross-linking, is relatively …
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Clinical study on the difference of binoculus biological parameters of the anterior segment in early keratoconus diagnosis
叶凡， 薛劲松 - qwer
… biological parameters of the anterior segment in subclinical keratoconus. Methods:
A retrospective case-control study. A total of 183 patients who visited our hospital
from March 2022 to November 2023 were included, including 107 cases in the …
A retrospective case-control study. A total of 183 patients who visited our hospital
from March 2022 to November 2023 were included, including 107 cases in the …
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[HTML] Correlation between Corneal Volume and Corneal Biomechanics and Corneal Volume Significance in Staging and Diagnosing Keratoconus
Z Wu, Y Zhang, Y Li, F Yang, X Su, Y Gao, S Wei, J Li - Journal of Ophthalmology, 2024
Purpose. To investigate the relationship between corneal volume (CV) at different
zones and corneal biomechanics in keratoconus (KC) along with the significance of
CV in diagnosing and staging KC. Methods. This prospective clinical study included …
zones and corneal biomechanics in keratoconus (KC) along with the significance of
CV in diagnosing and staging KC. Methods. This prospective clinical study included …
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New data reveals high prevalence of keratoconus in pediatric patients.
J Harthan - Optometry Times, 2024
A recent study conducted by the Illinois College of Optometry and the International
Keratoconus Academy of Eye Care Professionals found a higher prevalence of
keratoconus (KC) in pediatric patients than previously reported. The study used …
Keratoconus Academy of Eye Care Professionals found a higher prevalence of
keratoconus (KC) in pediatric patients than previously reported. The study used …
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[PDF] Ten-year incidence of keratoconus in relation to sex, age, and thyroid gland dysfunction: a nationwide population-based cohort study (2009–2018)
IK Chung, BS Kim, KD Han, YS Yoo, H Kim, C Jeong - Annals of Translational …, 2024
… predominance in keratoconus incidence and suggests a possible connection
between hyperthyroidism and keratoconus. Furthermore, it … differences in the
development of keratoconus and determined the incidence of clinically diagnosed …
between hyperthyroidism and keratoconus. Furthermore, it … differences in the
development of keratoconus and determined the incidence of clinically diagnosed …
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Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
E Gal, J Gispets, M Zyroff, E Netanya, L Gantz - … & physiological optics: the journal of the …
Introduction Soft contact lenses may be a good alternative for early-stage
keratoconus (KC) patients who do not tolerate rigid gas permeable (RGP) lenses
due to ocular discomfort or complications. This prospective study compared …
keratoconus (KC) patients who do not tolerate rigid gas permeable (RGP) lenses
due to ocular discomfort or complications. This prospective study compared …
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[HTML] Association of Novel Loci With Keratoconus Susceptibility in a Chinese Genome-Wide Association Study
L Xu, X Zheng, S Yin, K Yang, Q Fan, Y Gu, Y Yuan… - … Ophthalmology & Visual …, 2024
Purpose: Keratoconus (KC) is a progressive corneal disease that can lead to
corneal blindness if not properly managed. The purpose of this study was to identify
genetic associations with KC in China and to investigate whether these genetic …
corneal blindness if not properly managed. The purpose of this study was to identify
genetic associations with KC in China and to investigate whether these genetic …
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[HTML] Keratoconus presentation with respect to age, gender, and severity in Western India
ZA Shah, DM Purohit, PM Danayak, JD Patel… - Journal of Clinical …, 2024
Purpose: To study the demographic profile of keratoconus (KC) patients visiting a
tertiary eye care hospital in Western India. Materials and Methods: This cross-sectional,
observational study included newly diagnosed KC patients visiting our hospital …
tertiary eye care hospital in Western India. Materials and Methods: This cross-sectional,
observational study included newly diagnosed KC patients visiting our hospital …
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[PDF] Keratoconus in the West Region of Cameroon: Stakeholder knowledge and management
EN Ayukotang, VR Moodley, KP Mashige - African Vision and Eye Health, 2024
… Keratoconus is a multifaceted eye abnormality linked to both congenital and
ecological determinants. … 'We don't have machines to detect cases of keratoconus.
Not only that, I am the only one in this centre who is knowledgeable about …
ecological determinants. … 'We don't have machines to detect cases of keratoconus.
Not only that, I am the only one in this centre who is knowledgeable about …
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[HTML] Deep anterior lamellar keratoplasty in advanced keratoconus in children: A 4-year study
B Preethi, KK Kumar, N Malepati - Journal of Clinical Ophthalmology and Research, 2024
… anterior lamellar keratoplasty (DALK) in children and adolescents with advanced
keratoconus (KC) at a tertiary eye care center in India. … Deep anterior lamellar
keratoplasty (DALK) for advanced keratoconus (KC) in pediatric age group has seen …
keratoconus (KC) at a tertiary eye care center in India. … Deep anterior lamellar
keratoplasty (DALK) for advanced keratoconus (KC) in pediatric age group has seen …
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[HTML] Modulation transfer function and higher order aberrations with and without corneo scleral lens in an eye with keratoconus
S Shah, OH Pirdankar, LD Patil, S Sheth, P Jain… - Journal of Clinical …, 2024
… revealed right eye keratoconus and left eye was Forme fruste keratoconus. There
was a … irregularities arising from ectatic disorders such as keratoconus. Scleral
lenses are lenses to … ), Strehl ratio in addition to HOA with corneo-scleral contact …
was a … irregularities arising from ectatic disorders such as keratoconus. Scleral
lenses are lenses to … ), Strehl ratio in addition to HOA with corneo-scleral contact …
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[HTML] Quality and Readability of Online Information on Keratoconus in Portugal
C Costa, R Souza-Oliveira, J Gil, E Costa, C Tavares… - … Sociedade Portuguesa de …, 2024
INTRODUÇÃO: O queratocone é a ectasia corneana primária mais comum.
Atualmente, os doentes procuram na Internet respostas às suas expectativas em
termos de diagnóstico, tratamento e prognóstico. Porém, os sites não são filtrados …
Atualmente, os doentes procuram na Internet respostas às suas expectativas em
termos de diagnóstico, tratamento e prognóstico. Porém, os sites não são filtrados …
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[HTML] Controversies in the Management of Keratoconus
C Carriazo, MM Sinjab, C Liu, J Chhablani…
This book presents new technologies which are available now for the rehabilitation
of visual acuity in patients suffering from keratoconusand for arresting the
progression of this frustrating disease. All these current treatment options in differing …
of visual acuity in patients suffering from keratoconusand for arresting the
progression of this frustrating disease. All these current treatment options in differing …
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[PDF] Transcriptome RNA-Seq Analysis of Normal and Keratoconus Corneal Epithelium
FH Boshahma, MSM Solyman, M Ali, EA McDonnel… - 2024… plots were used to identify how characteristics impact development of keratoconus. …
and keratoconus development. Overexpression of peroxisome genes increases
phytanic acid levels, and causes Zellweger spectrum, affecting the cornea and …
and keratoconus development. Overexpression of peroxisome genes increases
phytanic acid levels, and causes Zellweger spectrum, affecting the cornea and …
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[PDF] Prospective study on the efficacy of RoseK2 contact lenses in the treatment of keratoconus: 59 patients
K Amine, L Robbana, S Hassina, N Tebbay… - J Clin Images Med Case …, 2024… We adapted corneal RPGCL (RoseK2 type) on 113 eyes of 59 patients with
keratoconus. The sex ratio was … Keratoconus geometry was closely correlated
with disease progression. This study confirms that RoseK2 RPGCLs are an effective …
keratoconus. The sex ratio was … Keratoconus geometry was closely correlated
with disease progression. This study confirms that RoseK2 RPGCLs are an effective …
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[PDF] Factors associated with keratoconus in Israel—A cross‐sectional population‐based study
O Ben‐Shaul, A Segal, S Schwartz, N Stein, M Hyams… - Acta Ophthalmologica, 2024
… keratoconus and fibromyalgia implied in a few case reports, we also investigated
the association between this chronic condition and keratoconus (… Further, the
study explored ethnicity as a risk factor for keratoconus and compared the prevalence …
the association between this chronic condition and keratoconus (… Further, the
study explored ethnicity as a risk factor for keratoconus and compared the prevalence …
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Alternative methods of surgical treatment of keratoconus
AV Tereshchenko, IG Trifanenkova, SK Demianchenko… - Vestnik oftalmologii, 2024
The introduction of early diagnostic methods for keratoconus into clinical practice
has become the basis for the development of surgical treatment techniques for this
pathology, such as corneal collagen crosslinking and interlamellar keratoplasty with …
has become the basis for the development of surgical treatment techniques for this
pathology, such as corneal collagen crosslinking and interlamellar keratoplasty with …
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Comparative analysis of clinical and functional parameters in patients with stable stage II-III keratoconus after implantation of corneal segments and fitting of scleral …
AT Khanjian, AV Ivanova, AS Sklyarova… - Vestnik oftalmologii, 2024
The modern treatment strategy for keratoconus (KC) involves sequential application
of medical technologies aimed at stabilizing pathological changes in the cornea and
restoring visual acuity. Purpose This study compares the effect of implantation of …
of medical technologies aimed at stabilizing pathological changes in the cornea and
restoring visual acuity. Purpose This study compares the effect of implantation of …
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[PDF] Corneal collagen cross-linking in patients with keratoconus from the Dresden protocol to customized solutions: theoretical basis
C Caruso, L D'Andrea, M Troisi, M Rinaldi, R Piscopo… - Int J Ophthalmol, 2024
● Keratoconus is an ectatic condition characterized by gradual corneal thinning,
corneal protrusion, progressive irregular astigmatism, corneal fibrosis, and visual
impairment. The therapeutic options regarding improvement of visual function …
corneal protrusion, progressive irregular astigmatism, corneal fibrosis, and visual
impairment. The therapeutic options regarding improvement of visual function …
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[HTML] Polygenic prediction of keratoconus and its measures: cross-sectional and longitudinal analyses in community-based young adults
SSY Lee, S Diaz-Torres, W He, S Yazar, E Chan… - American Journal of …, 2024
… Previous studies have validated a PRS for keratoconus in cross-sectional
analyses of older individuals. However, keratoconus typically affects younger adults.
This study thus explored the associations between keratoconus and its measures …
analyses of older individuals. However, keratoconus typically affects younger adults.
This study thus explored the associations between keratoconus and its measures …
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[HTML] Multi-modal imaging for the detection of early keratoconus: a narrative review
M Al Bdour, HM Sabbagh, HM Jammal - Eye and Vision, 2024
… Keratoconus is a common progressive corneal disorder that can be associated
with significant … disease, which include subclinical keratoconus and forme fruste
keratoconus, detection of such … for the detection of early cases of keratoconus …
with significant … disease, which include subclinical keratoconus and forme fruste
keratoconus, detection of such … for the detection of early cases of keratoconus …
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[HTML] Dual benefits of scleral lenses in collateral cases of Stevens-Johnson syndrome and Keratoconus-A case series
K Subramanian - Latin American Journal of Ophthalmology, 2024
Scleral lenses (SL) are larger diameter lenses that rest over the scleral, unlike the
corneal lenses. These lenses are fitted to not touch the cornea by creating a space
that will be filled with sterile isotonic fluid. Indications of SL include corneal ectatic …
corneal lenses. These lenses are fitted to not touch the cornea by creating a space
that will be filled with sterile isotonic fluid. Indications of SL include corneal ectatic …
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[HTML] Keratoconus Progression Determined at the First Visit: A Deep Learning Approach With Fusion of Imaging and Numerical Clinical Data
LM Hartmann, DS Langhans, V Eggarter, TJ Freisenich… - Translational Vision Science …, 2024
Purpose: Multiple clinical visits are necessary to determine progression of
keratoconus before offering corneal cross-linking. The purpose of this study was to
develop a neural network that can potentially predict progression during the initial …
keratoconus before offering corneal cross-linking. The purpose of this study was to
develop a neural network that can potentially predict progression during the initial …
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[PDF] AvaGen Genetic Testing versus Ocular Screening Assessments Including the Keratoconus Severity Score (KSS) and Randleman Ectasia Risk Score System (ERSS) …
M Moshirfar, S Pandya, S Zhang, IM Stoakes, A Ayesha… - Clinical Ophthalmology, 2024
Purpose To determine whether the AvaGen (AG) Genetic Eye Test provided
additional information for screening for the presence of keratoconus (KC) and
assessing KC risk in refractive surgery candidates, as compared to the Keratoconus …
additional information for screening for the presence of keratoconus (KC) and
assessing KC risk in refractive surgery candidates, as compared to the Keratoconus …
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The Chinese keratoconus (CKC) cohort study
K Yang, X Liu, L Xu, Y Gu, Q Fan, S Yin, Y Wang… - European Journal of …, 2024
… Keratoconus (KC) is a corneal disorder characterized by corneal thinning, blurred
vision, and irregular astigmatism, and KC eventually progresses to corneal
blindness if effective measures are not applied [1,2,3]. It affects both males and …
vision, and irregular astigmatism, and KC eventually progresses to corneal
blindness if effective measures are not applied [1,2,3]. It affects both males and …
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Refractive surgical approaches to keratoconus: A systematic review and network meta-analysis
S Niazi, F Doroodgar, SH Nazari, Y Rahimi… - Survey of Ophthalmology
Advancements in diagnostic methods and surgical techniques for keratoconus (KC)
have increased non-invasive treatment options. Successful surgical planning for KC
involves a combination of clinical science, empirical evidence, and surgical expertise …
have increased non-invasive treatment options. Successful surgical planning for KC
involves a combination of clinical science, empirical evidence, and surgical expertise …
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[HTML] Does collagen cross linking have any effect on retinal circulation in patients with keratoconus? An optical coherence tomography angiography (OCTA) study
S Bamdad, A Attar, M Fallahzadeh, F Ebrahimi… - BMC ophthalmology, 2024
Background We aimed to employ Optical Coherence Tomography Angiography (OCTA)
to comprehensively assess changes in the optic nerve head (ONH) and macular
perfusion before and after the Corneal Collagen Cross-Linking (CCL) procedure in …
to comprehensively assess changes in the optic nerve head (ONH) and macular
perfusion before and after the Corneal Collagen Cross-Linking (CCL) procedure in …
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Update on corneal crosslinking for keratoconus and corneal ectasia
SA Greenstein, PS Hersh - Current Opinion in Ophthalmology
… Performing CXL early to prevent progression and visual loss for our patients with
keratoconus is critical. This is especially important in the pediatric population when
progression of keratoconus can be rapid and severe. A recent study performed in a …
keratoconus is critical. This is especially important in the pediatric population when
progression of keratoconus can be rapid and severe. A recent study performed in a …
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[PDF] Artificial intelligence–can technology help predict the progression of keratoconus? A systematic review
S Watson, I Jiang, E Durakovic, H Kandel - 2024
… Studies were included if they were published in peer-reviewed journals, reported
at least one accuracy measure, and investigated keratoconus progression rather
than diagnosis or treatment efficacy. The outcome measures included accuracy in …
at least one accuracy measure, and investigated keratoconus progression rather
than diagnosis or treatment efficacy. The outcome measures included accuracy in …
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Image-and impression-based technology for scleral lens fitting for keratoconus: Efficiency of the fitting process
E Shorter, J Fogt, C Nau, J Harthan, A Nau… - Contact Lens and Anterior …, 2024
… keratoconus could streamline the fitting process by creating an initial lens based
upon the actual ocular surface shape rather than a standard diagnostic lens. This
study describes practitioner-reported efficiency of the SL fitting process of patients …
upon the actual ocular surface shape rather than a standard diagnostic lens. This
study describes practitioner-reported efficiency of the SL fitting process of patients …
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[HTML] A rare case of bilateral keratoconus and granular corneal dystrophy managed with contact lens
R Dutta, M Agarwal, M Subramanian, K Subramanian - Indian Journal of …, 2024
Keratoconus (KC) is a bilateral, non-inflammatory, progressive thinning disorder of
the cornea that results in high irregular astigmatism, distortion, and poor vision.
Granular corneal dystrophy (GCD) is an autosomal dominant stromal dystrophy with …
the cornea that results in high irregular astigmatism, distortion, and poor vision.
Granular corneal dystrophy (GCD) is an autosomal dominant stromal dystrophy with …
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Association of Vernal Keratoconjunctivitis (VKC) with Keratoconus in Patients Presenting to Ophthalmology Clinics of Rawal Institute of Health Sciences, Pakistan
M Zehra, MS Anwar, E Yousafzai, W Akhter, AM Rana - Pakistan Armed Forces …, 2024
… The disease severity, periodicity, and eye rubbing lead to the development of
keratoconus. Conclusion: Pediatric keratoconus deteriorates … early diagnosis,
recognition of progression, and appropriate intervention to prevent vision-threatening …
keratoconus. Conclusion: Pediatric keratoconus deteriorates … early diagnosis,
recognition of progression, and appropriate intervention to prevent vision-threatening …
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[HTML] Comparing the clinical applicability of wavefront phase imaging in keratoconus versus normal eyes
C Belda-Para, G Velarde-Rodríguez, M Velasco-Ocaña… - Scientific Reports, 2024
The aim of this work is to quantitatively assess the wavefront phase of keratoconic
eyes measured by the ocular aberrometer t· eyede (based on WaveFront Phase
Imaging Sensor), characterized by a lateral resolution of 8.6 µm without requiring …
eyes measured by the ocular aberrometer t· eyede (based on WaveFront Phase
Imaging Sensor), characterized by a lateral resolution of 8.6 µm without requiring …
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[PDF] Successful Collagen Crosslinking in Patients With Keratoconus and Systemic Scleroderma
A Alghamdi, EA Alghamdi, A Alghamdi, MM Abusayf… - Cureus, 2024
Scleroderma is an autoimmune disease that affects connective tissue. Keratoconus (KC)
is a rare ocular condition that may appear alongside scleroderma. Contact lenses
are an essential visual aid for KC patients, especially in advanced cases. However …
is a rare ocular condition that may appear alongside scleroderma. Contact lenses
are an essential visual aid for KC patients, especially in advanced cases. However …
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International Keratoconus Academy of Eye Care Professionals: A historical perspective: The collective enhances education, research, and quality of life.
SB Eiden, AS Morgenstern - Optometry Times, 2024
… of keratoconus management. The mission of IKA is to promote and develop
knowledge about the diagnosis and management of keratoconus and … IKA
focuses on education, research, and improving the quality of life for patients with …
knowledge about the diagnosis and management of keratoconus and … IKA
focuses on education, research, and improving the quality of life for patients with …
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Targeted next-generation sequencing analysis in Italian patients with keratoconus
M Lombardo, U Camellin, R Gioia, S Serrao, V Scorcia… - Eye, 2024
… Targeted NGS research provided new insights into the causative effect of candidate
genes in the clinical phenotype of keratoconus. Filaggrin mutations were found to
represent a genetic risk factor for development of progressive disease in Italy. … In a …
genes in the clinical phenotype of keratoconus. Filaggrin mutations were found to
represent a genetic risk factor for development of progressive disease in Italy. … In a …
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Implantable Collamer Lenses (ICL) for treating keratoconus
MA Al-Dabaat, R ِAbu Nassar, H Mesmar, S Amireh… - 2024
Purpose: Implantable Collamer Lens (ICL) implantation is a promising solution for
correcting refractive errors, particularly in advanced Keratoconus (KC). Despite its
increasing use, comprehensive data on its efficacy and complications remain limited …
correcting refractive errors, particularly in advanced Keratoconus (KC). Despite its
increasing use, comprehensive data on its efficacy and complications remain limited …
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[PDF] Diagnosis of Forme Fruste Keratoconus Using Corvis ST Sequences with Digital Image Correlation and Machine Learning
L Yang, K Qi, P Zhang, J Cheng, H Soha, Y Jin, H Ci… - Bioengineering, 2024
Purpose: This study aimed to employ the incremental digital image correlation (DIC)
method to obtain displacement and strain field data of the cornea from Corvis ST (CVS)
sequences and access the performance of embedding these biomechanical data …
method to obtain displacement and strain field data of the cornea from Corvis ST (CVS)
sequences and access the performance of embedding these biomechanical data …
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A pilot study on Langerhans cells in keratoconus patients by in vivo confocal microscopy before and after corneal cross-linking and correlation with eye rubbing
E Ferrini, C Posarelli, M Figus, D Lisi, G Gabbriellini - Contact Lens and Anterior Eye, 2024
Purpose The aim of this study was to investigate the corneal microstructure and
Langerhans cells using in vivo confocal microscopy in keratoconus patients before
and after cross-linking, and to correlate the morphologic findings with clinical and …
Langerhans cells using in vivo confocal microscopy in keratoconus patients before
and after cross-linking, and to correlate the morphologic findings with clinical and …
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Comparison between Anterior Segment Optical Coherence Tomography and pentacam in The Diagnosis of Keratoconus
AR Youssef, A Sharawy, AA Shebl - Benha Medical Journal, 2024
… keratoconus. This study aimed to compare the efficacy of Anterior Segment
Optical Coherence Tomography (AS-OCT) in detection of subclinical keratoconus …
the efficacy of AS-OCT in detection of subclinical keratoconus with the efficacy of the …
Optical Coherence Tomography (AS-OCT) in detection of subclinical keratoconus …
the efficacy of AS-OCT in detection of subclinical keratoconus with the efficacy of the …
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[HTML] Longitudinal Analysis of Corneal Biomechanics of Suspect Keratoconus: A Prospective Case-Control Study
Y Huo, X Chen, R Xie, J Li, Y Wang - Bioengineering, 2024
… indicator for the diagnosis of early keratoconus and suggested as a diagnostic
point for keratoconus by the global consensus on keratoconus; a PTE of >… The
SKC group included clinical keratoconus contralateral eye, having at least one …
point for keratoconus by the global consensus on keratoconus; a PTE of >… The
SKC group included clinical keratoconus contralateral eye, having at least one …
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Research progress of clinical application and complication of contact lens in keratoconus
REN Shengwei, FAN Qi, Y Kaili, LYU Tianbin - International Eye Science, 2024
… of early keratoconus can be corrected by spectacles. For the irregular astigmatism
of moderate to severe keratoconus, spectacles are no … contact lenses, the
application of contact lenses in different types of keratoconus, the complications of …
of moderate to severe keratoconus, spectacles are no … contact lenses, the
application of contact lenses in different types of keratoconus, the complications of …
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Keratoconus disease classification with multimodel fusion and vision transformer: a pretrained model approach
S Yaraghi, T Khatibi - BMJ open ophthalmology, 2024
… keratoconus image classification system that leverages multiple pretrained
models and a transformer architecture to achieve state-of-the-art performance in
detecting keratoconus… the accuracy of image classification models for keratoconus …
models and a transformer architecture to achieve state-of-the-art performance in
detecting keratoconus… the accuracy of image classification models for keratoconus …
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[PDF] New Developments in Corneal Cross-Linking for Keratoconus–Enhancing the Shape of the Cornea
R Herber, F Raiskup - 2024
Purpose. Corneal cross-linking (CXL) is an established treatment for corneal ectasia,
particularly keratoconus. The goal of the treatment is to stabilize the biomechanically
weakened cornea, thereby halting further progression of the disease and preventing …
particularly keratoconus. The goal of the treatment is to stabilize the biomechanically
weakened cornea, thereby halting further progression of the disease and preventing …
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Utility of Artificial Intelligence in the Diagnosis & Management of Keratoconus: A Systematic Review
D Goodman, AY Zhu - Frontiers in Ophthalmology
Introduction: The application of artificial intelligence (AI) systems in ophthalmology is
rapidly expanding. Early detection and management of keratoconus is important for
preventing disease progression and the need for corneal transplant. We review …
rapidly expanding. Early detection and management of keratoconus is important for
preventing disease progression and the need for corneal transplant. We review …
| | |
1162 Keratoconus in an Adolescent with Obstructive Sleep Apnea
J Purewal, A Jayakumar, I Perez - Sleep, 2024
… that occur during sleep and may contribute to the development of keratoconus.
Based on the IRIS Registry, the prevalence of keratoconus in adults is 2.9%
compared to 0.27% in pediatrics. We describe a pediatric patient with keratoconus …
Based on the IRIS Registry, the prevalence of keratoconus in adults is 2.9%
compared to 0.27% in pediatrics. We describe a pediatric patient with keratoconus …
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[HTML] Evaluation of dynamic corneal response parameters and the biomechanical E-staging after Intacs® SK implantation in keratoconus
E Flockerzi, T Berger, B Seitz, L Hamon, L Daas - Indian Journal of Ophthalmology, 2024
Purpose: This retrospective longitudinal study evaluated the biomechanical E-staging
in KC corneas before and after intracorneal ring segment (ICRS) implantation (Intacs®
SK, Addition Technology, Illinois, United States). Methods: Biomechanical E-staging …
in KC corneas before and after intracorneal ring segment (ICRS) implantation (Intacs®
SK, Addition Technology, Illinois, United States). Methods: Biomechanical E-staging …
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[HTML] The HUC progression score: A new method for determining KERATOCONUS progression
BL Eguileor, BS Zorrozúa, JE Ecenarro - European Journal of Ophthalmology, 2024
… Regarding the stage of keratoconus that progresses the most, our results suggest
that the mildest keratoconus is most likely to progress. This contrasts with other
studies which conclude that the greater the severity of keratoconus, the greater the …
that the mildest keratoconus is most likely to progress. This contrasts with other
studies which conclude that the greater the severity of keratoconus, the greater the …
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[PDF] Clinical profile of keratoconus in central India
R Gupta
… All Patients of Keratoconus without any previous interventions were included in
this study. Results: 129 eyes of 68 patients diagnosed with … Keratoconus causes
irregular astigmatism, leading to various degree of visual impairment.[5] Existing …
this study. Results: 129 eyes of 68 patients diagnosed with … Keratoconus causes
irregular astigmatism, leading to various degree of visual impairment.[5] Existing …
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Comparative analysis of the Agreement of Keratometry Readings across three devices in varying stages of Keratoconus: A Cross-Sectional Study
ΚΝ Παπαδόπουλος - 2024
The aim of the present thesis was to evaluate the agreement of keratometry (K)
readings obtained from three different devices-Pentacam HR, MS-39 and IOL-Master
700-across various grades of keratoconus. A cross-sectional analysis was …
readings obtained from three different devices-Pentacam HR, MS-39 and IOL-Master
700-across various grades of keratoconus. A cross-sectional analysis was …
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Immediate postoperative keratitis caused by Rhizopus species following standard CXL for keratoconus: A case report and literature review
A Venugopal, M Ravindran - European Journal of Ophthalmology, 2024
… He was diagnosed with progressive keratoconus in the right eye more than left
eye. After … to improve the biomechanical strength of the cornea in keratoconus.
The long-term safety and … edema, endothelial damage, and progression of …
eye. After … to improve the biomechanical strength of the cornea in keratoconus.
The long-term safety and … edema, endothelial damage, and progression of …
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Repeatability of epithelium thickness measured by an AS-OCT in different grades keratoconus and compared to AS-OCT/Placido topography
Y Wang, R Ning, K Li, H Xu, Y Li, Y Yang, I Gustafsson… - American Journal of …, 2024
… Considering the role of epithelial thickness in the diagnosis of keratoconus and
the fact that epithelium changes with the severity of KC, we believe that it is
necessary to investigate the accuracy of different devices in measuring ET. As far as …
the fact that epithelium changes with the severity of KC, we believe that it is
necessary to investigate the accuracy of different devices in measuring ET. As far as …
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Long-term results of accelerated corneal collagen crosslinking in paediatric patients with progressive keratoconus: 10-year follow-up
S Ahmet, G Yayla Akincilar, A Kirgiz… - Eye, 2024
… The Global Consensus on Keratoconus and Ectatic Diseases states that CCL is
extremely important in the treatment of keratoconus with … In our clinical practice,
we recommend ACCL in paediatric keratoconus patients as soon as the diagnosis is …
extremely important in the treatment of keratoconus with … In our clinical practice,
we recommend ACCL in paediatric keratoconus patients as soon as the diagnosis is …
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[PDF] OP-2 Bowman's layer in health, keratoconus and other corneal conditions
A Borgia, S Lawman, C Hart, M Posarelli, M Ahmed… - 2024
Purpose To investigate the central thickness of Bowman's layer in patients with
keratoconus, healthy cornea and other corneal conditions in relation to corneal
curvature and, epithelial and total corneal thickness in health, keratoconus (KC) and …
keratoconus, healthy cornea and other corneal conditions in relation to corneal
curvature and, epithelial and total corneal thickness in health, keratoconus (KC) and …
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OP-7 A comparison of keratoconus progression following collagen cross-linkage using standard or personalised keratometry thresholds
JPO Li, H Maile, C Bunce, M Leucci, B Allan, S Tuft… - 2024
… definitions of keratoconus progression … keratoconus eyes, with a variation of
Bland-Altman to determine the 95% regression-based limits of agreement (LoA). We
created Kaplan-Meier survival plots for standard and adaptive thresholds. The …
Bland-Altman to determine the 95% regression-based limits of agreement (LoA). We
created Kaplan-Meier survival plots for standard and adaptive thresholds. The …
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P-16 How to assess the effectiveness of corneal cross-linking for keratoconus: need of a shared protocol
M Ventura, M Airaldi, L Pagano, K Gadhvi, S Kaye… - 2024
Objective Comparing definitions of progression in keratoconus (KC) patients after
corneal cross-linking (CXL). Methods Retrospective case series of KC eyes
underwent CXL. Keratoconus progression after CXL treatment was defined based …
corneal cross-linking (CXL). Methods Retrospective case series of KC eyes
underwent CXL. Keratoconus progression after CXL treatment was defined based …
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[PDF] OP-6 The involvement of corneal nerves in the pathogenesis of keratoconus
M Al-Aqaba, H Dua - 2024
… of the involvement of corneal nerves in keratoconus and suggests further that they
may play … Objective To define if keratoconus progression estimates following
collagen cross-linkage (… We compared standard definitions of keratoconus progression …
may play … Objective To define if keratoconus progression estimates following
collagen cross-linkage (… We compared standard definitions of keratoconus progression …
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P-18 DMEK in ICE syndrome and keratoconus
Z Ashena, C Thaung - 2024
Case A 60-year-old male presented with gradual, painless deterioration of vision in
his left eye over four years. His past ophthalmic history was clear with no record of
trauma, surgery, infection or inflammation. His left eye's best corrected visual acuity (BCVA) …
his left eye over four years. His past ophthalmic history was clear with no record of
trauma, surgery, infection or inflammation. His left eye's best corrected visual acuity (BCVA) …
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Higher order aberrations in keratoconus
N Erdinest, N London, D Landau, R Barbara, A Barbara… - International Ophthalmology, 2024
… keratoconus has been described as a noninflammatory disease, reports of
associations with alterations in inflammatory mediators indicate that keratoconus
often … With the acceleration of refractive surgery, it is important to identify patients …
associations with alterations in inflammatory mediators indicate that keratoconus
often … With the acceleration of refractive surgery, it is important to identify patients …
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Functional Approach to IOL Selection in Eyes With Combined Cataract and Keratoconus With an Option for Refractive Lens Exchange
GJ Goebel, DA Price, MO Price, FW Price Jr - Journal of Refractive Surgery, 2024
… Although all of the eyes in this study had previously stable keratoconus and the
follow-up duration in our study was longer than in many prior reports (Table 3), it is
possible keratoconus could progress over a longer time period. The Holladay II …
follow-up duration in our study was longer than in many prior reports (Table 3), it is
possible keratoconus could progress over a longer time period. The Holladay II …
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[HTML] Artificial Neural Network for Automated Keratoconus Detection Using a Combined Placido Disc and Anterior Segment Optical Coherence Tomography Topographer
JLA Del Barrio, AM Eldanasoury, J Arbelaez, S Faini… - Translational Vision Science …, 2024
… versus keratoconus subjects class, and normal subjects versus keratoconus
suspect subjects class. For the sake of simplicity, we decided to omit abnormal and
myopic postoperative classes because the main aim of the study was the detection …
suspect subjects class. For the sake of simplicity, we decided to omit abnormal and
myopic postoperative classes because the main aim of the study was the detection …
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Differences Between Simulated Keratometry and Total Corneal Power in Eyes With Keratoconus and a Formula to Improve IOL Power Calculation Results
CP Coutinho, D Schiano-Lomoriello, C Mazzotta… - Journal of Refractive …, 2024
… calculation in eyes with keratoconus. Recent studies have shown that the results
are acceptable in eyes with stage I keratoconus (ie, those … proper formula is
chosen.9,10 On the other hand, in stage III keratoconus (ie, with keratometry > 53.00 …
are acceptable in eyes with stage I keratoconus (ie, those … proper formula is
chosen.9,10 On the other hand, in stage III keratoconus (ie, with keratometry > 53.00 …
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RiTe conjugate mediated corneal collagen crosslinking, a novel therapeutic intervention for keratoconus–In vitro and in vivo study
H Rohira, S Shankar, S Yadav, PP Srivastava… - International Journal of …, 2024
Corneal collagen crosslinking (CXL) is an effective method to halt the disease
progression of keratoconus, a progressive corneal dystrophy leading to cone
shaped cornea. Despite the efficacy of standard protocol, the concerning step of this …
progression of keratoconus, a progressive corneal dystrophy leading to cone
shaped cornea. Despite the efficacy of standard protocol, the concerning step of this …
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[PDF] Comparison of keratoplasty outcomes at the scar versus edema stages of keratoconus
Y Chen, Z You, C Wang, R Gao, K Zhang - Arq Bras Oftalmol, 2024
… Keratoconus is a dilated corneal disorder in which the local corneal stroma
becomes thinner, … Acute corneal edema is a keratoconus condition that results
from the Descemet membrane … This study examined the outcomes of two …
becomes thinner, … Acute corneal edema is a keratoconus condition that results
from the Descemet membrane … This study examined the outcomes of two …
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Corneal Endothelial Cell Volume Regulation Disorders in Keratoconus
IM Kuseina, LE Katkova, GS Baturina, IG Palchikova… - … ), Supplement Series A …, 2024
The study of the permeability to water and urea of plasma membranes of endothelial
cells of the normal cornea and cornea with a pronounced form of keratoconus was
carried out. Human corneal endothelial cells were obtained from surgical material …
cells of the normal cornea and cornea with a pronounced form of keratoconus was
carried out. Human corneal endothelial cells were obtained from surgical material …
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Evaluation of the results of contact lens assisted corneal cross-linking treatment in keratoconus patients with thin corneas
F Safalı, SY Ocak, BD Argon, G Karaca, MN Elçioğlu - Japanese Journal of …, 2024
Purpose We aimed to compare the efficacy and safety of accelerated contact lens-assisted
cross-linking (CA-CXL) with Lotrafilcon B and Comfilcon A lenses in keratoconus (KC)
patients with thin corneas. Study Design Retrospective, single-center study …
cross-linking (CA-CXL) with Lotrafilcon B and Comfilcon A lenses in keratoconus (KC)
patients with thin corneas. Study Design Retrospective, single-center study …
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[PDF] A novel posterior keratoconus with osteogenesis imperfecta by mutation in COL1A1
H Wu, X Shi, H Shi, L Liu, H Xu, L Hou, R Huang… - 2024
… Posterior keratoconus is a rare, non-progressive corneal condition in the posterior
surface of the cornea. Also known as keratoconus posticus, it is … The
manifestations in OI patients have not been well studied in the case of keratoconus …
surface of the cornea. Also known as keratoconus posticus, it is … The
manifestations in OI patients have not been well studied in the case of keratoconus …
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Retracted: Keratoconus Classification with Convolutional Neural Networks Using Segmentation and Index Quantification of Eye Topography Images by Particle …
BMR International - BioMed Research International, 2024
Retracted: Keratoconus Classification with Convolutional Neural Networks Using
Segmentation and Index Quantification of Eye Topography Images by Particle Swarm
Optimisation - PMC … Retracted: Keratoconus Classification with Convolutional Neural …
Segmentation and Index Quantification of Eye Topography Images by Particle Swarm
Optimisation - PMC … Retracted: Keratoconus Classification with Convolutional Neural …
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… Retinal Blood Vessel Densities Measured by Optical Coherence Tomography Angiography in Keratoconus Patients Are Negatively Correlated with Keratoconus …
MD Leclaire, JJ Storp, L Lahme, EL Esser, N Eter… - Diagnostics, 2024
… Keratoconus (KC) is the most common corneal ectasia. Optical coherence
tomography angiography (OCT-A) is a relatively new non-invasive imaging technique
that allows the visualization and quantification of retinal and choriocapillary blood …
tomography angiography (OCT-A) is a relatively new non-invasive imaging technique
that allows the visualization and quantification of retinal and choriocapillary blood …
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[HTML] Criteria for patient selection and indication for intracorneal ring segments in keratoconus
A Vega, JL Alió - Eye and Vision, 2024
… to classify keratoconus [5]. In this publication, we aim to propose a better
approach of different treatments that are available for keratoconus … term result
after ICR implantation in the treatment of keratoconus, we decided to study patients …
approach of different treatments that are available for keratoconus … term result
after ICR implantation in the treatment of keratoconus, we decided to study patients …
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[HTML] Balanced activation of Nrf-2/ARE mediates the protective effect of sulforaphane on keratoconus in the cell mechanical microenvironment
R Liu, R Ma, X Yan - Scientific Reports, 2024
Keratoconus (KC) is a progressive degenerative disease that usually occurs
bilaterally and is characterized by corneal thinning and apical protrusion of the
cornea. Oxidative stress is an indicator of the accumulation of reactive oxygen …
bilaterally and is characterized by corneal thinning and apical protrusion of the
cornea. Oxidative stress is an indicator of the accumulation of reactive oxygen …
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[PDF] Keratoconus: exploring fundamentals and future perspectives–a comprehensive systematic review
S Niazi, Z Gatzioufas, F Doroodgar, O Findl… - Therapeutic Advances in …, 2024
… Artificial intelligence has changed how we treat the eye disease keratoconus in
recent years. This study examines the many keratoconus therapies available, … The
idea behind using artificial intelligence is to help patients see better and treat …
recent years. This study examines the many keratoconus therapies available, … The
idea behind using artificial intelligence is to help patients see better and treat …
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Barriers to the Diagnosis and Management of Keratoconus Among Optometrists in Kenya [Response to Letter]
ZA Rashid, VR Moodley, KP Mashige, KE Agho - Clinical Optometry, 2024
We reviewed the Letter to the Editor by Mahdi Sadeghi and Sabrina Shahid which
refers to our published article "Barriers to the Diagnosis and Management of
Keratoconus Among Optometrists in Kenya" 1 and their interest is noted. However …
refers to our published article "Barriers to the Diagnosis and Management of
Keratoconus Among Optometrists in Kenya" 1 and their interest is noted. However …
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Efficacy comparison of combining cross-linking and refractive laser ablation in progressive keratoconus: a network meta-analysis of short-term outcomes and systemic …
A Achiron, T Yahalomi, B Knyazer, I Hecht, U Elbaz… - Canadian Journal of …, 2024
Purpose This study aimed to assess the effect of combining corneal collagen cross-linking
(CXL) with refractive laser ablation techniques for the treatment of keratoconus, a
progressive corneal disorder. Methods We performed a systematic review and meta-analysis …
(CXL) with refractive laser ablation techniques for the treatment of keratoconus, a
progressive corneal disorder. Methods We performed a systematic review and meta-analysis …
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Quantitative evaluation of morphological and functional changes in meibomian glands and lipid layer thickness in patients with and without keratoconus
X Hou, C Liu, Y Luo, N Yu, P Chen, J Zhuang, K Yu - Graefe's Archive for Clinical and …, 2024
… In this prospective, cross-sectional study, 164 eyes of 164 keratoconus patients
and 64 eyes of 64 age-matched control subjects were included. … of keratoconus.
Gland diameter may be a sensitive functional morphology metric of meibomian …
and 64 eyes of 64 age-matched control subjects were included. … of keratoconus.
Gland diameter may be a sensitive functional morphology metric of meibomian …
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Outcomes of accelerated corneal cross-linking for pediatric and adult keratoconus: a comparative study
A Bustamante-Arias, JC Hernandez-Camarena… - International Ophthalmology, 2024
Purpose To compare the visual, refractive, and topographic outcomes of a high
irradiance accelerated corneal crosslinking (ACXL) protocol after a 12-month follow-up
between pediatric and adult patients with progressive keratoconus (KC). Methods …
irradiance accelerated corneal crosslinking (ACXL) protocol after a 12-month follow-up
between pediatric and adult patients with progressive keratoconus (KC). Methods …
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The effect of transepithelial corneal collagen cross-linking treatment on optical quality of the cornea in keratoconus: 12-month clinical results
S Kaya Ergen, S Subaşı, B Yılmaz Tuğan, N Yüksel… - International Ophthalmology, 2024
… least 400 mm and axial topography pattern consistent with keratoconus. All 67
patients in the study were diagnosed with progressive keratoconus. The presence of
at least one of the following criteria was considered as progressive keratoconus: An …
patients in the study were diagnosed with progressive keratoconus. The presence of
at least one of the following criteria was considered as progressive keratoconus: An …
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The effect of the Interocular Difference in Blur on Binocular Vision in Keratoconus
BL Marella - 2024
… Phase reversals due to HOAs in keratoconus deteriorated stereoacuity (t>3.479, p<0.007) …
In conclusion, the eye with lesser disease severity dominates binocular viewing in
keratoconus. … factors (contrast and phase shifts) could partially restore the …
In conclusion, the eye with lesser disease severity dominates binocular viewing in
keratoconus. … factors (contrast and phase shifts) could partially restore the …
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[HTML] Keratoconus: Tailored contact lens solutions optimise vision
V Wang, M Ziaei
… A family history of keratoconus, eczema, asthma, eye rubbing, allergy, Down
syndrome and other collagen vascular disorders are risk factors for developing
keratoconus. Patients at risk, particularly those with a family history, should be …
syndrome and other collagen vascular disorders are risk factors for developing
keratoconus. Patients at risk, particularly those with a family history, should be …
| | | |
[PDF] Genetic investigation in a four-generation Chinese family with congenital fibrosis of extraocular muscles and keratoconus
Q Lin, X Wang, X Zhan, X Peng, Y Wang, X Zhou - Heliyon, 2024
Here, we have reported the genetic and clinical characteristics of four generations of
a family patient from China with congenital fibrosis of extraocular muscles 1 (CFEOM1)
and keratoconus (KC). The history of diseases, clinical observations, and blood …
a family patient from China with congenital fibrosis of extraocular muscles 1 (CFEOM1)
and keratoconus (KC). The history of diseases, clinical observations, and blood …
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[HTML] The candidate proteins associated with keratoconus: A meta-analysis and bioinformatic analysis
T Song, J Song, J Li, H Ben Hilal, X Li, P Feng, W Chen - PloS one, 2024
Purpose Keratoconus (KC) is a multifactorial disorder. This study aimed to conduct a
systematic meta-analysis to exclusively explore the candidate proteins associated
with KC pathogenesis. Methods Relevant literature published in the last ten years in …
systematic meta-analysis to exclusively explore the candidate proteins associated
with KC pathogenesis. Methods Relevant literature published in the last ten years in …
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Clinical study of normal, keratoconus, and post-surgical corneas with phase decorrelation OCT
BJ Blackburn, L Asroui, I Tarib, D Dunukara… - Ophthalmic Technologies …, 2024
Several important diseases and treatments of the cornea present primarily on a
micromechanical level. Here, a technique called temporal phase decorrelation OCT
is used to observe micromechanical weakening in the cornea after refractive surgery …
micromechanical level. Here, a technique called temporal phase decorrelation OCT
is used to observe micromechanical weakening in the cornea after refractive surgery …
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[HTML] Central and peripheral corneal sagittal height in keratoconus and healthy eyes
M Larrosa, J Gispets, N Lupón, G Cardona, A Sempere - Contact Lens and Anterior …, 2024
… peripheral z values were larger in keratoconus, rotational variations were
comparable between keratoconus and healthy eyes, suggesting that large diameter
spherical rigid corneal contact lenses may be an alternative to scleral lenses in …
comparable between keratoconus and healthy eyes, suggesting that large diameter
spherical rigid corneal contact lenses may be an alternative to scleral lenses in …
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[PDF] Schirmer test type I evaluation before and after collagen cross linking for treatment of keratoconus
KAELA GabAllah, MF Saleh, SAM Farid
… of keratoconus conditions using isotonic Riboflavin and Ultraviolet-A light. This
comparative study included 60 patients suffering from keratoconus. … There are
improvements in Schirmer test results after 6 months of CXL for treatment of …
comparative study included 60 patients suffering from keratoconus. … There are
improvements in Schirmer test results after 6 months of CXL for treatment of …
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[HTML] Severe ulcerative keratopathy following implantation of an acellular porcine corneal stromal lenticule in a patient with keratoconus
T Berger, U Schlötzer-Schrehardt, F Flockerzi, L Daas… - Contact Lens and Anterior …, 2024
Purpose To report a case of ulcerative keratopathy following implantation of
acellular porcine corneal stroma (APCS) in a patient with keratoconus (KC).
Methods A 58 year-old patient initially presented with an ulcerative keratopathy in …
acellular porcine corneal stroma (APCS) in a patient with keratoconus (KC).
Methods A 58 year-old patient initially presented with an ulcerative keratopathy in …
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High-Fluence Epithelium-off Accelerated Pulsed Corneal Cross-linking (15 mW/cm2; 7.2 J/cm2) for Pediatric Keratoconus: A 3-Year Retrospective Analysis
R Fasciani, L Scartozzi, S Bruzio, G Di Stefano… - Journal of Refractive …, 2024
… CXL for progressive keratoconus was first introduced by Wollensak et al6 in 2003.
It is the first suc- cessful treatment modality to stop the progression of keratoconus by
increasing the intrinsic corneal biomechanical stability. Their original standard CXL …
It is the first suc- cessful treatment modality to stop the progression of keratoconus by
increasing the intrinsic corneal biomechanical stability. Their original standard CXL …
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[PDF] Prevalence of Keratoconus in the Young Eastern Population of Saudi Arabia
A Khattak, A Altalhi, AB Alotaibi, AM Khattak - Cureus, 2024
Background: Keratoconus (KCN) is a progressive corneal ectasia that manifests at a
young age and significantly impacts vision and quality of life. Early diagnosis allows
for effective treatment with corneal collagen crosslinking, yet there is a lack of …
young age and significantly impacts vision and quality of life. Early diagnosis allows
for effective treatment with corneal collagen crosslinking, yet there is a lack of …
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Scheimpflug-Based Tomographic Risk Factors for the Development of Acute Corneal Hydrops in Keratoconus.
SN Yu, R Gad, R Kutler, D Trief - Cornea, 2024
Purpose The purpose of this study was to assess the risk factors that predispose
patients with keratoconus to develop acute corneal hydrops (ACH), including both
clinical and tomographic risk factors. We additionally describe tomographic changes …
patients with keratoconus to develop acute corneal hydrops (ACH), including both
clinical and tomographic risk factors. We additionally describe tomographic changes …
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Estimated prevalence of keratoconus in the largest metropolitan area of Italy
M Lombardo, D Alunni Fegatelli, S Serrao, A Vestri… - European Journal of …, 2024
… This study reported a high estimated prevalence of keratoconus in a metropolitan
area of Italy, as found in recent studies in the Mediterranean and Middle East
countries. Screening for keratoconus is highly recommendable and easily feasible …
area of Italy, as found in recent studies in the Mediterranean and Middle East
countries. Screening for keratoconus is highly recommendable and easily feasible …
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Relationship between Conjunctival Impression Cytology, the Type of Eye Rubbing and the Stages of Keratoconus
LA Rodriguez, SE Guerrero, LA Rodriguez-Gutierrez… - 2024
… Keratoconus is a multifactorial disease where eye rubbing plays an important role
in disease progression. Persistent eye rubbing may … the index and middle finger
can lead to advanced stages of keratoconus. Keratoconus stage IV was associated …
in disease progression. Persistent eye rubbing may … the index and middle finger
can lead to advanced stages of keratoconus. Keratoconus stage IV was associated …
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[HTML] Mendelian Randomisation Analysis of Causal Association between Lifestyle, Health Factors, and Keratoconus
J Cheng, L Yang, Y Ye, L He, S Chen, J Wang - Bioengineering, 2024
Keratoconus (KC), a leading cause of vision impairment, has an unclear aetiology.
This study used Mendelian randomization (MR) to explore the causal links between
various factors (smoking, asthma, Down syndrome, inflammatory bowel disease …
This study used Mendelian randomization (MR) to explore the causal links between
various factors (smoking, asthma, Down syndrome, inflammatory bowel disease …
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[HTML] Differences in anterior chamber depth in keratoconus patients with binocular very asymmetry ectasia
Z Wang, H Ma, Y Zhang, Y Yuan, Y Liu, Y Chen - BMC ophthalmology, 2024
… Keratoconus is a noninflammatory ectatic corneal disorder that is commonly
bilateral and usually asymmetrical, in which the ectatic cornea … and treatment of
keratoconus, and there are few studies of anterior chamber characteristics in the …
bilateral and usually asymmetrical, in which the ectatic cornea … and treatment of
keratoconus, and there are few studies of anterior chamber characteristics in the …
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M Nicholson, VM Singh, S Murthy, D Gatinel, S Pereira… - Indian Journal of …, 2024
This review analyzed all pertinent articles on keratoconus (KCN) and cataract
surgery. It covers preoperative planning, intraoperative considerations, and
postoperative management, with the aim of providing a simplified overview of …
surgery. It covers preoperative planning, intraoperative considerations, and
postoperative management, with the aim of providing a simplified overview of …
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[PDF] Barriers to the Diagnosis and Management of Keratoconus Among Optometrists in Kenya
ZA Rashid, VR Moodley, KP Mashige, KE Agho - Clinical Optometry, 2024
Background Early diagnosis and management of keratoconus (KC) are important for
limiting visual complications of the disease. This study aimed to explore the
perspectives of optometrists on the barriers to effective diagnosis and management …
limiting visual complications of the disease. This study aimed to explore the
perspectives of optometrists on the barriers to effective diagnosis and management …
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[PDF] Variants in the ZNF469 gene in families with Brittle cornea syndrome and keratoconus
Q Lin, X Wang, T Han, X Peng, X Zhou - Heliyon, 2024
… variants and keratoconus. We recruited a four-generation BCS1 family and two
keratoconus families to explore pathogenic ZNF469 variants. Methods: This study
included 11 members from a family with BCS1, 2 families with keratoconus, 368 …
keratoconus families to explore pathogenic ZNF469 variants. Methods: This study
included 11 members from a family with BCS1, 2 families with keratoconus, 368 …
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[PDF] Spike sign–To predict the formation of big bubble in deep anterior lamellar keratoplasty in advanced keratoconus
S D'Souza, R Shetty - Indian Journal of Ophthalmology, 2024
Lamellar surgeries have revolutionized our understanding and practice of
keratoplasties. However, the learning curve in deep anterior lamellar keratoplasty (DALK)
makes it daunting for novice surgeons. This paper describes a unique intraoperative …
keratoplasties. However, the learning curve in deep anterior lamellar keratoplasty (DALK)
makes it daunting for novice surgeons. This paper describes a unique intraoperative …
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[HTML] Outcomes of 320-degree intrastromal corneal ring segment implantation for advanced keratoconus
NN Chen, CC Sun - Taiwan Journal of Ophthalmology, 2024
PURPOSE: The purpose of this study is to investigate visual and tomographic
outcomes and complications of long-arc length intrastromal corneal ring segment (ICRS)
implantation for the treatment of advanced keratoconus. MATERIALS AND …
outcomes and complications of long-arc length intrastromal corneal ring segment (ICRS)
implantation for the treatment of advanced keratoconus. MATERIALS AND …
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[HTML] In Vivo Evaluation of Corneal Biomechanics Following Cross-Linking Surgeries Using Optical Coherence Elastography in a Rabbit Model of Keratoconus
Y Zhao, Y Zhu, Y Yan, H Yang, J Liu, Y Lu, Y Li… - Translational Vision Science …, 2024
… biomechanics of an in vivo keratoconus model, and keratoconus after CXL
treatments in vivo. We discuss the biomechanical properties of the in vivo
keratoconus model and evaluate the changes in the biomechanical properties of the …
treatments in vivo. We discuss the biomechanical properties of the in vivo
keratoconus model and evaluate the changes in the biomechanical properties of the …
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[HTML] Biomechanical changes in keratoconus after customized stromal augmentation
S Niazi, JA del Barrio, F Doroodgar, A Sanginabadi… - Taiwan Journal of …, 2024
… Diagnostic ability of corneal shape and biomechanical parameters for detecting
frank keratoconus. Cornea 2018;37:1025‑34. 10. … Comparison of different corneal
imaging modalities using artificial intelligence for diagnosis of keratoconus: A …
frank keratoconus. Cornea 2018;37:1025‑34. 10. … Comparison of different corneal
imaging modalities using artificial intelligence for diagnosis of keratoconus: A …
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A Cross-Sectional Analysis to Assess the Role of Atopy in Keratoconus Among Saudi Population [Corrigendum]
II Abuallut, AR Alomaish, AM Arishy, MA Mashragi… - International Journal of …, 2024
The International Journal of General Medicine is an international, peer-reviewed
open-access journal that focuses on general and internal medicine, pathogenesis,
epidemiology, diagnosis, monitoring and treatment protocols. The journal is …
open-access journal that focuses on general and internal medicine, pathogenesis,
epidemiology, diagnosis, monitoring and treatment protocols. The journal is …
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Differentially expressed microRNAs targeting genes in key pathways in keratoconus
DM Nowak-Malczewska, J Swierkowska, M Gajecka - Frontiers in Genetics
Introduction: Keratoconus (KTCN) is a corneal ectasia, characterized by a
progressive thinning and protrusion of the cornea, with a complex etiology involving
genetic, behavioral, lifestyle, and environmental factors. Previous studies indicated …
progressive thinning and protrusion of the cornea, with a complex etiology involving
genetic, behavioral, lifestyle, and environmental factors. Previous studies indicated …
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[HTML] Expression of Tissue Inhibitors of Metalloproteinases (TIMP-1, TIMP-2, TIMP-3, TIMP-4) in Blood Serum of Patients with Keratoconus
M Nowak-Wąs, P Wąs, Z Czuba, R Wojnicz… - Journal of Clinical Medicine, 2024
… Clinical keratoconus was diagnosed in 134 eyes and subclinical keratoconus in
32 companion eyes. The severity of keratoconus was assessed based on the Amsler–Krumeich
classification. Most eyes with keratoconus showed the first or second degree of …
32 companion eyes. The severity of keratoconus was assessed based on the Amsler–Krumeich
classification. Most eyes with keratoconus showed the first or second degree of …
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[PDF] Descemetic Deep Anterior Lamellar Keratoplasty versus Penetrating Keratoplasty in Advanced Keratoconus: Comparison of Visual and Refractive Outcomes
L Spadea, L Di Genova, E Trovato Battagliola… - Therapeutics and Clinical …, 2024
… This study enrolled eyes affected by keratoconus with preoperative mean
keratometry ≥60 diopters (D) that were treated with either Descemetic DALK (30
eyes) or PK (29 eyes) by using always the same corneal diameters (8.00mm …
keratometry ≥60 diopters (D) that were treated with either Descemetic DALK (30
eyes) or PK (29 eyes) by using always the same corneal diameters (8.00mm …
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Diagnostic Importance of OCT Pachymetry in Keratoconus
KK Benca, M Javorka, R Vida, J Halička, M Kralik… - Ceska a slovenska …, 2024
Aims To demonstrate changes in distance and near fusional vergence measured
with prism bars, while compensating for present heterophoria using current
ametropia correction. In addition, to determine the differences in values of the AC/A …
with prism bars, while compensating for present heterophoria using current
ametropia correction. In addition, to determine the differences in values of the AC/A …
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[PDF] Evaluation of ocular surface features following corneal collagen cross-linking treatment in keratoconus patients: 24-month results
GS Vural, ES Sari, A Yazici, C Guler
… For this reason, we followed ocular surface parameters in keratoconus patients
until 24 months after CXL and compared them with pre-… The keratoconus patients
who have Grade 1 or 2 keratoconus according to the Amsler-Krumeich keratoconus …
until 24 months after CXL and compared them with pre-… The keratoconus patients
who have Grade 1 or 2 keratoconus according to the Amsler-Krumeich keratoconus …
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Pediatric keratoconus epidemiology: a systematic scoping review
LO Hansen, R Garcia, FB Cresta, AAM Torricelli… - International Ophthalmology, 2024
Background Pediatric keratoconus (pediatric KC) causes progressive deformation of
the cornea in children and adolescents, leading to a gradual loss of vision and a
need for rehabilitation. However, new treatments may halt the disease and prevent …
the cornea in children and adolescents, leading to a gradual loss of vision and a
need for rehabilitation. However, new treatments may halt the disease and prevent …
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Revisiting rabbit models for keratoconus: A long-term study on collagenase-induced disease progression
S Shankar, M Thacker, A Sahoo, AR Aindla, KR Padala… - Experimental Eye Research, 2024
Keratoconus (KC) is one of the degenerative corneal disorders consequential of
degradation of network of collagen fibrils in cornea leading to thinning and cone
shaped cornea. Various studies have established animal models of KC by inducing …
degradation of network of collagen fibrils in cornea leading to thinning and cone
shaped cornea. Various studies have established animal models of KC by inducing …
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Detecting Keratoconus in Primary Healthcare: What general practitioners could do? Poster Presentation-Case Report-General practitioner
MK Akbar, CP Samira - Ophthalmologica Indonesiana, 2023
… Children with keratoconus experience faster disease progression and significant
visual impairment at diagnosis, impacting their quality of … keratoconus with
amblyopia and was referred to an ophthalmologist for further examination and …
visual impairment at diagnosis, impacting their quality of … keratoconus with
amblyopia and was referred to an ophthalmologist for further examination and …
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CAN RIGID GAS PERMEABLE (RGP) CONTACT LENS BE THE BEST OPTION FOR A KERATOCONUS PATIENT? Poster Presentation-Case Report-Resident
DF DWIMARTA, ANI ISMAIL, EVA KUMALASARI - Ophthalmologica Indonesiana, 2023
Introduction : Keratoconus is a condition of cone-shaped cornea caused by stromal
thinning. This disorder leads to visual disturbance due to irregular astigmatism,
myopia, and corneal protrusion. A severe irregular astigmatism must be corrected by …
thinning. This disorder leads to visual disturbance due to irregular astigmatism,
myopia, and corneal protrusion. A severe irregular astigmatism must be corrected by …
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Rigid Gas Permeable (RGP) as Keratoconus Management After Corneal Collagen Cross-Linking (CXL) Procedure: a Case Report: Poster Presentation-Case Report …
MLA Sanusi, K Satari, JS Hutabarat, IR Musa, SN Sirait - Ophthalmologica …, 2023
… are the mainstay for keratoconus patients and widely used. This case report
presents RGP as a management for keratoconus after Corneal Collagen Cross-
Linking (CXL) procedure. Case Illustration : A 22-year-old woman diagnosed with …
presents RGP as a management for keratoconus after Corneal Collagen Cross-
Linking (CXL) procedure. Case Illustration : A 22-year-old woman diagnosed with …
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Corneal Collagen Cross-Linking (CXL) in Pediatric Keratoconus: Changes in Visual Acuity and Biomechanical Properties: Visual Acuity and Biomechanical Properties
G Sulaksmono - Ophthalmologica Indonesiana, 2023
Abstract Introduction & Objectives : Keratoconus is a progressive disease that
changes the … study that included all pediatric keratoconus patients without any
underlying disease that … Overall, CXL was safe and significantly improve UCVA …
changes the … study that included all pediatric keratoconus patients without any
underlying disease that … Overall, CXL was safe and significantly improve UCVA …
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Intrastromal corneal ring segments for keratoconus patients: up to 12 years follow up
M Al Bdour, M Abu-Ameerh, A Gharaibeh, R AlQudah… - International Ophthalmology, 2024
… This study represents the largest follow up for ICRS implanted in keratoconus
patients. Improvement of … keratoconus patients recruited from 2008 to 2010 and
underwent ICRS implantation. In this study, we reported the long-term outcome of …
patients. Improvement of … keratoconus patients recruited from 2008 to 2010 and
underwent ICRS implantation. In this study, we reported the long-term outcome of …
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[HTML] Binocular vision parameters and visual performance in bilateral keratoconus corrected with spectacles versus rigid gas-permeable contact lenses
LF Barba–Gallardo, LM Jaramillo-Trejos… - Journal of Optometry, 2024
Purpose To analyze binocular vision of individuals aged 18 to 35 years diagnosed
with keratoconus, utilizing spectacles and rigid gas-permeable (RGP) contact lenses.
Research was led by the Universidad Autónoma de Aguascalientes, México and …
with keratoconus, utilizing spectacles and rigid gas-permeable (RGP) contact lenses.
Research was led by the Universidad Autónoma de Aguascalientes, México and …
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[PDF] Keratoconus characteristics and associations: A cross-sectional keratoconus study in western India (CKSWI)
Z Shah, D Purohit, P Danayak - Indian Journal of Ophthalmology, 2024
Purpose: To study the clinical and tomographic characteristics and associations of
keratoconus (KC) patients visiting a tertiary eye care hospital. Methods: This was a
cross-sectional, observational study that included 242 newly diagnosed clinical KC …
keratoconus (KC) patients visiting a tertiary eye care hospital. Methods: This was a
cross-sectional, observational study that included 242 newly diagnosed clinical KC …
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Transepithelial Accelerated Crosslinking for Progressive Keratoconus: A Critical Analysis of Medium-Term Treatment Outcomes
R Vilares-Morgado, AM Ferreira, AM Cunha, R Moreira… - Clinical Ophthalmology, 2024
… Keratoconus treatment has improved significantly in recent years, with the
development of … , in patients with progressive keratoconus who underwent a
single treatment of TE-ACXL. … Retrospective, single-center, observational, cohort …
development of … , in patients with progressive keratoconus who underwent a
single treatment of TE-ACXL. … Retrospective, single-center, observational, cohort …
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[HTML] A current review on keratoconus
G Lahkar, G Paul - Journal of Ophthalmic Research and Practice, 2023
… Subclinical keratoconus is a term used to describe an eye having topographic
signs of keratoconus with normal corneal slit-lamp findings, … decreased in
keratoconus. It is a valuable tool to differentiate forme fruste keratoconus from …
signs of keratoconus with normal corneal slit-lamp findings, … decreased in
keratoconus. It is a valuable tool to differentiate forme fruste keratoconus from …
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Assessment of Health Disparities and Barriers to Accessing Keratoconus and Crosslinking at a Tertiary Referral Center
L Angelo, A Gokul, H Wadhwa, CNJ McGhee, M Ziaei - Cornea, 2024
… Keratoconus is a progressive noninflammatory corneal ectasia, often diagnosed
during youth. This disease process causes the cornea to … and successful
treatment for preventing the progression of keratoconus. Keratoconus typically …
during youth. This disease process causes the cornea to … and successful
treatment for preventing the progression of keratoconus. Keratoconus typically …
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[HTML] Accelerated Corneal Cross-linking in Pediatric Patients with Progressive Keratoconus: 12-Month Follow-up Results
S Dervişoğulları, A Pelit - Nigerian Journal of Clinical Practice, 2024
… In this study, case series of patients 18 years old or younger with progressive
keratoconus who underwent accelerated CXL were observed. All consecutive
patients underwent accelerated CXL with setting of 9 mW/cm 2 for 10-minute …
keratoconus who underwent accelerated CXL were observed. All consecutive
patients underwent accelerated CXL with setting of 9 mW/cm 2 for 10-minute …
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[HTML] A Novel approach for Corneal Remodeling of Laser Asymmetric Keratectomy with Collagen Cross Linking in Patients with Keratoconus Suspect
JS Min, D Lee, SS Lee, PM Min - The Open Ophthalmology Journal, 2024
Background True Keratoconus Suspect (KCS) is an absolute contraindication to
LASIK or Photorefractive Keratectomy (PRK) due to postoperative ectasia. Objective
To evaluate the effectiveness of laser asymmetric keratectomy with collagen cross-linking …
LASIK or Photorefractive Keratectomy (PRK) due to postoperative ectasia. Objective
To evaluate the effectiveness of laser asymmetric keratectomy with collagen cross-linking …
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[PDF] Comparative posterior corneal profile of keratoconus hydrops versus Haab's striae in congenital glaucoma
S Mandal, A Singh, S Sen, JS Titiyal, V Gupta, S Gupta - Indian Journal of Ophthalmology
Keratoconus eyes develop corneal decompensation more often compared to eyes
with primary congenital glaucoma (PCG) following Descemet's membrane (DM) tear.
This study was conducted to compare the posterior corneal morphology in areas …
with primary congenital glaucoma (PCG) following Descemet's membrane (DM) tear.
This study was conducted to compare the posterior corneal morphology in areas …
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[PDF] Analysis of Scheimpflug Tomography Parameters for Detecting Subclinical Keratoconus in the Fellow Eyes of Patients with Unilateral Keratoconus in the Eastern …
A Al Somali, H Najmi, H Alsawadi, H Alsawadi… - Clinical Ophthalmology, 2024
… Normal fellow eyes in patients with unilateral keratoconus were found to exhibit
the mildest form of subclinical keratoconus. The … keratoconus and normal eyes,
implying the need for multimodal imaging techniques for the optimal early detection …
the mildest form of subclinical keratoconus. The … keratoconus and normal eyes,
implying the need for multimodal imaging techniques for the optimal early detection …
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Toward Keratoconus Diagnosis: Dataset Creation and AI Network Examination
P Ghorbani, MJ Ahmadi, SS Naseri, M Keshavarz… - 2023 11th RSI International …, 2023
… Diagnosing keratoconus (KC) is essential due to its effect on refractive surgeries
like LASIK … AI can significantly assist in the automatic and accurate diagnosis of
keratoconus. For this … This method facilitates an accurate diagnosis of …
like LASIK … AI can significantly assist in the automatic and accurate diagnosis of
keratoconus. For this … This method facilitates an accurate diagnosis of …
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AI-Driven Keratoconus Detection: Integrating Medical Insights for Enhanced Diagnosis
M Keshavarz, MJ Ahmadi, SS Naseri, P Ghorbani… - 2023 11th RSI International …, 2023
… of keratoconus as a main ocular disorder is imperative for reducing the risk of
vision blurring and potential blindness. Additionally, keratoconus (… This study
introduces an image dataset acquired by the Pentacam device, which is commonly …
vision blurring and potential blindness. Additionally, keratoconus (… This study
introduces an image dataset acquired by the Pentacam device, which is commonly …
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[HTML] Lenticule addition keratoplasty for the treatment of keratoconus: A systematic review and critical considerations
Y Liu, Y He, Y Deng, L Wang - Indian Journal of Ophthalmology, 2024
… Keratoconus is a corneal disorder characterized by the progressive thinning and
bulging of … as conventional surgical methods for advanced keratoconus are
limited by relatively high rates … Keratoconus is a multifactorial disease …
bulging of … as conventional surgical methods for advanced keratoconus are
limited by relatively high rates … Keratoconus is a multifactorial disease …
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[PDF] A Comparison of Black and Non-Black Patients in the Presentation and Treatment of Keratoconus
M Christensen, J Kartchner, M Giegengack… - Clinical Ophthalmology, 2024
Purpose Patients with advanced keratoconus (KCN) are less likely to benefit from
corneal cross-linking and may require a partial or full thickness keratoplasty. This
study aimed to determine whether racial disparities exist in the clinical presentation …
corneal cross-linking and may require a partial or full thickness keratoplasty. This
study aimed to determine whether racial disparities exist in the clinical presentation …
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[HTML] Headache Attributed to Refractive Error: Improvement after Topography-Guided Photorefractive Keratectomy with Corneal Cross-Linking in Patients with Keratoconus
NTH Khoo, B Burgos-Blasco, A Antoniou, B Jenkins… - Journal of Clinical Medicine, 2024
… to refractive errors (HARE) in keratoconus. Methods: Patients diagnosed with
keratoconus undergoing TGPRK for refractive correction were … Conclusions:
Surgical correction of irregular astigmatism in patients with keratoconus can …
keratoconus undergoing TGPRK for refractive correction were … Conclusions:
Surgical correction of irregular astigmatism in patients with keratoconus can …
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[HTML] In vivo confocal microscopy evaluation of infiltrated immune cells in corneal stroma treated with cell therapy in advanced keratoconus
M El Zarif, K Abdul Jawad, JL Alió, N Makdissy… - Journal of Ophthalmic …, 2024
This study investigates immune cell (ICs) infiltration in advanced keratoconus
patients undergoing autologous adipose-derived adult stem cell (ADASC) therapy
with recellularized human donor corneal laminas (CL). A prospective clinical trial …
patients undergoing autologous adipose-derived adult stem cell (ADASC) therapy
with recellularized human donor corneal laminas (CL). A prospective clinical trial …
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[HTML] Mini review: human clinical studies of stem cell therapy in keratoconus
M Ahadi, S Ramin, A Abbasi, H Tahmouri, SB Hosseini - BMC ophthalmology, 2024
… , there are limited clinical studies in keratoconus. These studies showed
promising results of … In this article, we tried to review different aspects of
keratoconus stem cell therapy, including … of keratoconus, the goal of intrastromal …
promising results of … In this article, we tried to review different aspects of
keratoconus stem cell therapy, including … of keratoconus, the goal of intrastromal …
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[HTML] Improving early detection of keratoconus by Non Contact Tonometry. A computational study and new biomarkers proposal
E Redaelli, M Nana, B Calvo, JFR Matas, G Luraghi… - Journal of the Mechanical …, 2024
… Keratoconus is a progressive ocular disorder affecting the corneal tissue, leading
to irregular astigmatism and decreased visual acuity. The architectural organization
of corneal tissue is altered in keratoconus, … and improve the diagnosis of …
to irregular astigmatism and decreased visual acuity. The architectural organization
of corneal tissue is altered in keratoconus, … and improve the diagnosis of …
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[HTML] … Changes of Cornea Volume Measured by Means of Anterior Segment-Optical Coherence Tomography in Patients with Stable and Progressive Keratoconus
S Vaccaro, C Vivarelli, AC Yu, N Pecora, G Lionetti… - Life, 2024
… Consecutive patients affected by keratoconus were evaluated by means of
anterior segment-optical coherence … keratoconus eyes have yet to be investigated,
we sought to evaluate, over time, these modifications in patients with both stable and …
anterior segment-optical coherence … keratoconus eyes have yet to be investigated,
we sought to evaluate, over time, these modifications in patients with both stable and …
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[HTML] Genetic variants in the FOXO1 and ZNF469 genes are associated with keratoconus in Sweden: a case-control study
W Wonneberger, B Sterner, U MacLean, M Claesson… - BMC Ophthalmology, 2024
Keratoconus (KC) is characterized by pathological thinning and bulging of the
cornea that may lead to visual impairment. The etiology of sporadic KC remains
enigmatic despite intensive research in recent decades. The purpose of this study …
cornea that may lead to visual impairment. The etiology of sporadic KC remains
enigmatic despite intensive research in recent decades. The purpose of this study …
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Keratoconus: Ocular surface considerations, from bench to bedside
F Doroodgar, S Niazi - Acta Ophthalmologica, 2024
Aims/Purpose: This comprehensive systematic narrative study is aimed to describe
the close interactions between the ocular surface and keratoconus with its vast
spectrum of diagnostic and treatment techniques, both basic and clinical. Methods …
the close interactions between the ocular surface and keratoconus with its vast
spectrum of diagnostic and treatment techniques, both basic and clinical. Methods …
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Is it really keratoconus‐topographic mimicry
A Wykrota, B Seitz, E Flockerzi - Acta Ophthalmologica, 2024
… keratoconus configuration, but in which objectifiable no keratoconus exists and
thus a so-called pseudo-keratoconus is present. … Conclusions: This case series
shows that different corneal pathologies can imitate a topographic keratoconus …
thus a so-called pseudo-keratoconus is present. … Conclusions: This case series
shows that different corneal pathologies can imitate a topographic keratoconus …
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Morphogeometric characterization in keratoconus according to the RETICS grading system
CPT Jaimes, E Megiddo, C Gomez, A Moya… - Acta Ophthalmologica, 2024
… Aims/Purpose: Keratoconus progression characterizes by corneal thinning
resulting in irregular astigmatism and visual impairment. In the … variables in
healthy corneas and keratoconus. RETICS grading system was used to characterize …
resulting in irregular astigmatism and visual impairment. In the … variables in
healthy corneas and keratoconus. RETICS grading system was used to characterize …
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Comparison of waveform‐derived ORA parameters in clinical keratoconus, subclinical keratoconus and healthy subjects
K Atay, O Özalp, E Atalay - Acta Ophthalmologica, 2024
Aims/Purpose: The aim of this study was to comparison of waveform‐derived Ocular
Response Analyser (ORA) parameters in clinical keratoconus (KC), subclinical
keratoconus (SKC) and healthy subjects. Methods: This retrospective comparative …
Response Analyser (ORA) parameters in clinical keratoconus (KC), subclinical
keratoconus (SKC) and healthy subjects. Methods: This retrospective comparative …
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Repeatability of ANTERION in subjects with keratoconus
MS Larraz, A Blasco‐Martinez - Acta Ophthalmologica, 2024
… Aims/Purpose: The aim of this study was to study the repeatability of ANTERION
in subjects diagnosed with keratoconus. Methods: The subjects selected had a
previous diagnosis of keratoconus. These subjects were divided into three groups …
in subjects diagnosed with keratoconus. Methods: The subjects selected had a
previous diagnosis of keratoconus. These subjects were divided into three groups …
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Big data enabled keratoconus care
JPO Li - Acta Ophthalmologica, 2024
… Keratoconus is a disorder affecting the cornea in which its normal round shape …
keratoconus getting worse. However there is limited reports of its long term safety in
large numbers and we reported one of the largest series in the world. We used data …
keratoconus getting worse. However there is limited reports of its long term safety in
large numbers and we reported one of the largest series in the world. We used data …
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Deep learning in early keratoconus/corneal ectasia
A Langenbucher - Acta Ophthalmologica, 2024
… Early detection of keratoconus in a screening environment is crucial as in this
stage several therapeutic options such as collagen … In this talk we focus on new
techniques of automatic identification of ectatic corneal diseases such as …
stage several therapeutic options such as collagen … In this talk we focus on new
techniques of automatic identification of ectatic corneal diseases such as …
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The biomechanical e‐staging—In vivo assessment of corneal biomechanics in keratoconus
E Flockerzi, R Vinciguerra, MW Belin, P Vinciguerra… - Acta Ophthalmologica, 2024
Aims/Purpose: Keratoconus (KC) is biomechanically characterized by a decreased
resistance to deformation when compared to healthy corneas. The aim of this
presentation is to give an overview about the development and clinical application of …
resistance to deformation when compared to healthy corneas. The aim of this
presentation is to give an overview about the development and clinical application of …
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In‐vivo evaluation of corneal collagen fibrils pattern to detect Keratoconus
C Ancona, ML Passaro, M Airaldi, E Lipari, F Semeraro… - Acta Ophthalmologica, 2024
Aims/Purpose: The corneal stroma, is formed by fibrous connective tissue containing
collagen fibrils that are super‐organized in lamellae. In keratoconus (KC), intra‐lamellar
and inter‐lamellar disrupted organization causes a progressive thinning and corneal …
collagen fibrils that are super‐organized in lamellae. In keratoconus (KC), intra‐lamellar
and inter‐lamellar disrupted organization causes a progressive thinning and corneal …
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Peripheral sterile corneal infiltrate after cross linking in keratoconus: A case report
R Ayad, D Ghizlane, R Chahir, L Ajdour - Acta Ophthalmologica, 2024
Aims/Purpose: The aim of our work is to describe the clinical aspect of sterile corneal
infiltrates after cross linking and to evaluate the risk factors involved in their
occurrence. Methods: We report the case of a young girl, followed for bilateral …
infiltrates after cross linking and to evaluate the risk factors involved in their
occurrence. Methods: We report the case of a young girl, followed for bilateral …
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[PDF] Influence of corneal diameter on the accuracy of corneal tomography in patients with forme fruste keratoconus or thin corneas
L Ding, L Niu, W Shi, X Zhou, Y Qian - Clinical and Experimental Optometry, 2024
… on the diagnostic accuracy of Pentacam tomographic indices in eyes with forme
fruste keratoconus (FFKC) and thin corneas. … of keratoconus suspicion. However,
owing to the ambiguity of the definition, there are no definitive criteria to help …
fruste keratoconus (FFKC) and thin corneas. … of keratoconus suspicion. However,
owing to the ambiguity of the definition, there are no definitive criteria to help …
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[PDF] Keratoconus Treatment Using Femtosecond Laser–Assisted Innovative Intracorneal Ring–Supported Graft Surgery: A Pilot Investigation
K Jadidi, JL Alió, SA Mosavi, F Nejat, H Aghamolaei… - Journal of Refractive …, 2024
… keratoconus and its progression, there is still a need for ways to better reshape
the cornea, further improve visual acuity, and halt the progression of keratoconus. …
Moreover, ICR insertion can only be used for mild to moderate keratoconus, and is …
the cornea, further improve visual acuity, and halt the progression of keratoconus. …
Moreover, ICR insertion can only be used for mild to moderate keratoconus, and is …
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[HTML] Analysis of Cytokine and Chemokine Level in Tear Film in Keratoconus Patients before and after Corneal Cross-Linking (CXL) Treatment
M Krok, E Wróblewska-Czajka, O Łach-Wojnarowicz… - International Journal of …, 2024
Keratoconus (KC) is a degenerative corneal disorder whose aetiology remains
unknown. The aim of our study was to analyse the expressions of cytokines and
chemokines in KC patients before and after specified time intervals after corneal …
unknown. The aim of our study was to analyse the expressions of cytokines and
chemokines in KC patients before and after specified time intervals after corneal …
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Tomographic characteristics of keratoconus in a sample of Yemeni patients Featured
MA Al-Ansi, NA Aldhaigi, HA Alakhlee
Background: Keratoconus is a non-inflammatory disorder that leads to visual
impairment. Early diagnosis and treatment save the vision of the patients. Aim: This
study aimed to identify tomographic characteristics of keratoconus in Yemeni patient …
impairment. Early diagnosis and treatment save the vision of the patients. Aim: This
study aimed to identify tomographic characteristics of keratoconus in Yemeni patient …
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[HTML] Patterns in refractive error and treatment delay in keratoconus–An Australian study
S Bobba, A Wood, J Males, Y Kerdraon - Plos one, 2024
Keratoconus is the most common primary corneal ectasia and is associated with
significant morbidity. In its early stages, keratoconus is often … Early diagnosis of
keratoconus facilitates timely referral for treatments such as corneal collagen cross-linking …
significant morbidity. In its early stages, keratoconus is often … Early diagnosis of
keratoconus facilitates timely referral for treatments such as corneal collagen cross-linking …
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Accuracy of intraocular lens power formulas in eyes with keratoconus: Multi-center study in Japan
T Yokogawa, Y Mori, H Torii, S Goto, Y Hasegawa… - Graefe's Archive for Clinical …, 2024
… The MAE of the Barrett True-K for keratoconus, Kane keratoconus, and Kane
formulas … Keratoconus-specific formulas were more accurate than existing
formulas in Japanese eyes. The Barrett True-K formula for keratoconus had higher …
formulas … Keratoconus-specific formulas were more accurate than existing
formulas in Japanese eyes. The Barrett True-K formula for keratoconus had higher …
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[PDF] Balanced Activation of Nrf-2/ARE Mediates Sulforaphane's Protective Effect on Keratoconus in Cell Mechanical Microenvironment
R Liu, R Ma, X Yan - 2024
Keratoconus (KC) is a progressive degenerative disease that usually occurs
bilaterally and is characterized by corneal thinning and the apical protrusion of the
cornea. Oxidative stress is an indication of the accumulation of reactive oxygen …
bilaterally and is characterized by corneal thinning and the apical protrusion of the
cornea. Oxidative stress is an indication of the accumulation of reactive oxygen …
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[PDF] Longitudinal Evaluation of Biomechanical Indices in Fellow Eyes of Patients With Keratoconus Classified as Having Very Asymmetric Ectasia With Normal Topography
B Kovalchuk, R Khoramnia, HS Son, J Meis, P Winkler… - Journal of Refractive …, 2024
… keratoconus registered in the keratoconus registry at the University Eye Clinic
Heidelberg between October 2020 and October 2022. A total of 513 patients with
keratoconus … unilateral keratoconus and fellow eyes with tomographically regular …
Heidelberg between October 2020 and October 2022. A total of 513 patients with
keratoconus … unilateral keratoconus and fellow eyes with tomographically regular …
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M Khan, A Ageed - Cureus, 2024
Keratoconus (KC) incidence is on the increase. The advent of corneal-collagen cross-linking
(CXL) has revolutionized the management of KC. This systematic review looks at the
efficacy and complications of two novel treatments within CXL: Epithelial-On (Epi-On) …
(CXL) has revolutionized the management of KC. This systematic review looks at the
efficacy and complications of two novel treatments within CXL: Epithelial-On (Epi-On) …
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[PDF] Awareness of Keratoconus and Its Relationship With Eye Rubbing Among the Population of the Eastern Province of Saudi Arabia
A AlSomali, D Almithn, A Alamer, A Al-Omair… - Cureus, 2024
… Aim: This study aims to assess the awareness level of keratoconus and its
relation to eye rubbing … keratoconus among participants in the Eastern Province of
Saudi Arabia, our research revealed a total of 101 (26%) participants had an overall …
relation to eye rubbing … keratoconus among participants in the Eastern Province of
Saudi Arabia, our research revealed a total of 101 (26%) participants had an overall …
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[HTML] Keratoconus cone location influences ocular biomechanical parameters measured by the Ocular Response Analyzer
PT Yuhas, MM Fortman, AM Mahmoud, CJ Roberts - Eye and Vision, 2024
Background Keratoconus is characterized by asymmetry in the biomechanical
properties of the cornea, with focal weakness in the area of cone formation. We
tested the hypothesis that centrally-measured biomechanical parameters differ …
properties of the cornea, with focal weakness in the area of cone formation. We
tested the hypothesis that centrally-measured biomechanical parameters differ …
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[HTML] Artificial intelligence as diagnostic modality for keratoconus: A systematic review and meta-analysis
A Afifah, F Syafira, PM Afladhanti, D Dharmawidiarini - Journal of Taibah University …, 2024
Artificial intelligence (AI) has been utilized to enhance diagnostic management and
guide treatment. The use of AI as a sophisticated diagnostic modality has not only
improved the feature of cornea evaluation in ocular imaging but also has unlocked …
guide treatment. The use of AI as a sophisticated diagnostic modality has not only
improved the feature of cornea evaluation in ocular imaging but also has unlocked …
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[HTML] Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium
R Ning, Y Wang, Z Xu, I Gustafsson, J Li, G Savini… - Eye and Vision, 2024
… repeatability of the measurements and the keratoconus disease severity, the
repeatability was assessed in patients with varying degrees of keratoconus [22, 23].
Here, we provided cut-off criteria for the assessment of progressive patients with …
repeatability was assessed in patients with varying degrees of keratoconus [22, 23].
Here, we provided cut-off criteria for the assessment of progressive patients with …
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[HTML] Keratoconus overview: History, etiology, and diagnosis
A Morgenstern - 2023
… Keratoconus is a disease of the cornea that, if left untreated, can lead to loss of
vision, decrease in quality of life, and potentially blindness. As optometrists, we are
the gatekeepers of the management of keratoconus, … Patients who present with …
vision, decrease in quality of life, and potentially blindness. As optometrists, we are
the gatekeepers of the management of keratoconus, … Patients who present with …
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[HTML] Comparative evaluation of methods for obtaining the stress-free geometry of keratoconus corneas with different levels of severity
C Gómez, DP Piñero, JL Alió, F Cavas - Computers in Biology and Medicine, 2023
… The patient-specific 3D geometric modelling used in this study for each
keratoconus severity grade was generated from a finite and discrete set of points
acquired by the Sirius tomograph vision algorithm (spatial point clouds …
keratoconus severity grade was generated from a finite and discrete set of points
acquired by the Sirius tomograph vision algorithm (spatial point clouds …
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[HTML] Unilateral progressive keratoconus associated with ipsilateral craniofacial fibrous dysplasia treated with corneal cross-linking
AC Jiang, M Indaram - American Journal of Ophthalmology Case Reports, 2023
… In this report, we describe a case of unilateral keratoconus associated with
ipsilateral polyostotic fibrous dysplasia of the left frontal bone and orbital roof that
underwent successful stabilization of keratoconus progression after corneal …
ipsilateral polyostotic fibrous dysplasia of the left frontal bone and orbital roof that
underwent successful stabilization of keratoconus progression after corneal …
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[PDF] Identification of Comparative Collagen Fibril Associated Changes in Normal and Keratoconus Corneas using Vibrational Optical Coherence Tomography and …
FH Silver, D Benedetto, T Deshmukh, NA Daher - Med Discover-ies, 2023
Vibrational Optical Coherence Tomography (VOCT) is a non-invasive technique that
uses infrared light and audible sound to characterize tissues noninvasively. We
have used VOCT in vivo to characterize the differences between control corneas …
uses infrared light and audible sound to characterize tissues noninvasively. We
have used VOCT in vivo to characterize the differences between control corneas …
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